Evidence map›Paper›PMID 40650025›Full record

ArticleInternational journal of molecular sciences2025

Synthesis and Transformation of Tricyclic KYNA Derivatives.

Julián Robin Sárik, István Szatmári, Bálint Lőrinczi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julián Robin SárikInstitute of Pharmaceutical Chemistry, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary.ORCID 0009-0001-7127-0361
István SzatmáriInstitute of Pharmaceutical Chemistry, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary.ORCID 0000-0002-8571-5229
Bálint LőrincziInstitute of Pharmaceutical Chemistry, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary.ORCID 0000-0001-7773-0034

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kynurenic acid (KYNA) derivatives condensed with an aromatic ring (tricyclic KYNA derivatives) have been successfully synthesized, and the reactivity of these analogues has been investigated in the modified Mannich reaction resulting in new Mannich bases. The

Indexed as

Antineoplastic AgentsAntiviral AgentsKynurenic AcidHumansMannich BasesMolecular StructureAntineoplastic AgentsAntiviral AgentsKynurenic AcidMannich BasesConrad–Limpach synthesisKYNAMannich-reactiontricyclic KYNA derivatives

Identifiers

PMID40650025
PMCPMC12250539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.