Evidence map›Paper›PMID 40649944›Full record

ReviewInternational journal of molecular sciences2025

Primary Plasma Cell Leukemia: Recent Advances in Molecular Understanding and Treatment Approaches.

Ichiro Hanamura, Sivasundaram Karnan, Akinobu Ota, Akiyoshi Takami

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ichiro HanamuraDivision of Hematology, Department of Internal Medicine, Aichi Medical University, Nagakute 480-1195, Japan.ORCID 0000-0002-6681-8927
Sivasundaram KarnanDepartment of Biochemistry, Aichi Medical University, Nagakute 480-1195, Japan.ORCID 0000-0003-2165-7565
Akinobu OtaDepartment of Food and Nutritional Environment, College of Human Life and Environment, Kinjo Gakuin University, Nagoya 463-8521, Japan.ORCID 0000-0002-6296-2921
Akiyoshi TakamiDivision of Hematology, Department of Internal Medicine, Aichi Medical University, Nagakute 480-1195, Japan.ORCID 0000-0002-1822-9976

Funding

The Ministry of Education, Culture, Sports and Technology of Japan 25K11678
6 · The paper itself

Abstract

Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia. According to revised diagnostic criteria, pPCL is defined by the presence of ≥5% circulating plasma cells (CPCs) in the peripheral blood of patients with newly diagnosed multiple myeloma (NDMM). pPCL is characterized by a distinct cytogenetic profile, including frequent t(11;14),

Indexed as

Leukemia, Plasma CellHematopoietic Stem Cell TransplantationHumansPrognosis14)bispecific antibodiesCAR-Tcirculating plasma cellsplasma cell leukemiat(11venetoclax

Identifiers

PMID40649944
PMCPMC12250127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.