ArticleInternational journal of molecular sciences2025
Phosphorus-Derived Isatin Hydrazones: Synthesis, Structure, Thromboelastography, Antiplatelet, and Anticoagulation Activity Evaluation.
Aleksandr V Samorodov, Wang Yi, Dmitry A Kudlay, Elena A Smolyarchuk, Alexey B Dobrynin, Ayrat R Khamatgalimov, Karina Shchebneva, Marina Kadomtseva, Dilbar Komunarova, Anna G Strelnik and 1 more
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In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Aleksandr V SamorodovDepartment of Pharmacology, Bashkir State Medical University, Lenin St. 3, Ufa 450008, Russia.ORCID 0000-0001-9302-499X Wang YiSchool of Pharmacy, Hangzhou Normal University, Yuhangtan, 2318, Hangzhou 310030, China.
Dmitry A KudlayDepartment of Pharmacology, Sechenov First Moscow State Medical University (Sechenov University), Bolshaya Pirogovskaya St. 2, Building 4, Moscow 119435, Russia.
Elena A SmolyarchukDepartment of Pharmacology, Sechenov First Moscow State Medical University (Sechenov University), Bolshaya Pirogovskaya St. 2, Building 4, Moscow 119435, Russia.ORCID 0000-0002-2615-7167 Alexey B DobryninArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.ORCID 0000-0002-4912-3699 Ayrat R KhamatgalimovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.ORCID 0000-0002-2865-8619 Karina ShchebnevaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Marina KadomtsevaA.M. Butlerov Institute of Chemistry, Kazan Federal University, Kremlevskaya St. 29, Kazan 420008, Russia.
Dilbar KomunarovaDepartment of Organic Chemistry, Kazan National Research Technological University, Sibirsky Trakt 12, Kazan 420029, Russia.
Anna G StrelnikArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Andrei V BogdanovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Funding
National Natural Science Foundation of China 82361138563Russian Science Foundation 24-45-00071
6 · The paper itselfAbstract
A series of new isatin hydrazones bearing phosphorus-containing moiety was synthesized through a simple, high-yield and easy work-up reaction of phosphine oxide (Phosenazide) or phosphinate (2-chloroethyl (4-(dimethylamino)phenyl)(2-hydrazinyl-2-oxoethyl)phosphinate, CAPAH) hydrazides with aryl-substituted isatins. The
Indexed as
AnticoagulantsHydrazonesIsatinPhosphorusPlatelet Aggregation InhibitorsAnimalsHumansMolecular StructureThrombelastographyAnticoagulantsHydrazonesIsatinPhosphorusPlatelet Aggregation Inhibitorsantithrombotic activitycrystal structurehemostasishydrazonesisatinphosphorus
Identifiers
PMID40649924
PMCPMC12249729
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