Evidence map›Paper›PMID 40649857›Full record

ArticleInternational journal of molecular sciences2025

Cortisol-Induced Chromatin Remodeling and Gene Expression in Skeletal Muscle of Rainbow Trout: Integrative ATAC-Seq and RNA-Seq Analysis.

Rodrigo Zuloaga, Camila Garrido, Luciano Ahumada-Langer, José Luis Galaz, Giorgia Daniela Ugarte, Alfredo Molina, Juan Antonio Valdés

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rodrigo ZuloagaPrograma de Doctorado en Biotecnología, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.ORCID 0000-0002-7820-7509
Camila GarridoLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Luciano Ahumada-LangerLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.ORCID 0009-0002-6400-3449
José Luis GalazLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Giorgia Daniela UgarteLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Alfredo MolinaLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.ORCID 0000-0002-7411-5391
Juan Antonio ValdésLaboratorio de Biotecnología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1230794
6 · The paper itself

Abstract

Cortisol, the main glucocorticoid in teleost, plays a central role in mediating the physiological response to stress by regulating metabolism, immune function, and growth. While its transcriptional effects are well known, its role in modulating chromatin accessibility in fish skeletal muscle remains poorly understood. In this study, we investigated the epigenomic and transcriptomic changes induced by cortisol in a juvenile rainbow trout's (

Indexed as

Chromatin Assembly and DisassemblyGene Expression RegulationHydrocortisoneMuscle, SkeletalOncorhynchus mykissAnimalsChromatin Immunoprecipitation SequencingGene Expression ProfilingRNA-SeqTranscriptomeHydrocortisoneATAC-seqcortisolrainbow troutRNA-seqstress response

Identifiers

PMID40649857
PMCPMC12250572

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.