Evidence map›Paper›PMID 40649814›Full record

ArticleInternational journal of molecular sciences2025

Proteomic Characterization of Human Peripheral Blood Mononuclear Cells Exposed to a 50 Hz Magnetic Field.

Massimo Bracci, Raffaella Lazzarini, Francesco Piva, Matteo Giulietti, Elena Marinelli Busilacchi, Elisa Rossi, Fabio Di Criscio, Lory Santarelli, Antonella Poloni

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Massimo BracciDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.ORCID 0000-0003-3901-5376
Raffaella LazzariniDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.
Francesco PivaDepartment of Specialistic Clinical and Odontostomatological Sciences, Polytechnic University of Marche, Monte d'Ago, 60131 Ancona, Italy.
Matteo GiuliettiDepartment of Specialistic Clinical and Odontostomatological Sciences, Polytechnic University of Marche, Monte d'Ago, 60131 Ancona, Italy.
Elena Marinelli BusilacchiDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.ORCID 0000-0002-0693-3376
Elisa RossiDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.
Fabio Di CriscioDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.
Lory SantarelliDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.ORCID 0000-0003-1015-7098
Antonella PoloniDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.ORCID 0000-0002-4221-4125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to extremely low-frequency magnetic fields (ELF-MF) can induce biological alterations in human cells, including peripheral blood mononuclear cells (PBMCs). However, the molecular mechanisms and key regulatory factors underlying this cellular response remain largely unknown. In this study, we analyzed the proteomic profiles of PBMCs isolated from three human subjects. PBMCs were exposed to 50 Hz, 1 mT of ELF-MF for 24 h and compared to unexposed PBMCs from the same individuals. ELF-MF exposure altered the expression levels of several PBMC proteins without affecting cell proliferation, cell viability, or cell cycle progression. A total of 51 proteins were upregulated, 36 of which were intercorrelated and associated with the

Indexed as

Leukocytes, MononuclearMagnetic FieldsProteomeProteomicsAdultCell ProliferationCell SurvivalHumansMaleProteomeELF-MFimmune functionmetabolic pathwaysmitochondrial ADP/ATP transportPBMCsproteomic profile

Identifiers

PMID40649814
PMCPMC12250113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.