Evidence map›Paper›PMID 40649754›Full record

ArticleInternational journal of molecular sciences2025

Exploring the Therapeutic Potential of

Cheng-Liang Peng, Chun-Tang Chen, I-Chung Tang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Efficacy and safety of Lutetium-177 (Annals of nuclear medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cheng-Liang PengDepartment of Isotope Application Research, National Atomic Research Institute, Taoyuan 325207, Taiwan.ORCID 0000-0001-7130-0260
Chun-Tang ChenDepartment of Isotope Application Research, National Atomic Research Institute, Taoyuan 325207, Taiwan.
I-Chung TangDepartment of Isotope Application Research, National Atomic Research Institute, Taoyuan 325207, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second leading cause of cancer-related death in men, with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases representing a critical clinical challenge. Although radium-223 (Ra-223) is approved for treating mCRPC with bone metastases, its efficacy remains limited, necessitating the development of more effective therapies. This study investigates the therapeutic potential of

Indexed as

Bone NeoplasmsDipeptidesHeterocyclic Compounds, 1-RingLutetiumProstatic NeoplasmsRadioisotopesRadiopharmaceuticalsAnimalsCell Line, TumorDisease Models, AnimalHumansMaleMiceProstate-Specific AntigenProstatic Neoplasms, Castration-ResistantTissue DistributionDipeptidesHeterocyclic Compounds, 1-RingLutetiumLutetium-177Prostate-Specific AntigenPSMA-617RadioisotopesRadiopharmaceuticals177Lu-PSMA-617bone metastasispreclinical modelprostate cancertargeted radionuclide therapy

Identifiers

PMID40649754
PMCPMC12250129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.