ReviewMolecules (Basel, Switzerland)2025
Hydrazides as Powerful Tools in Medicinal Chemistry: Synthesis, Reactivity, and Biological Applications.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Enhancing the Conjugation of Cyclotriphosphazene Covalent Organic Frameworks to Improve the Fluorescence Detection Performance of Hydrazine.Journal of fluorescence · 2026Article
- Synthesis and molecular characterization of a novel FA-ADH-GMS conjugated pH-responsive lipid for targeted drug delivery.Molecular diversity · 2026Article
- New benzimidazole-alkanesulfonate conjugates as cholinesterase inhibitors with in vitro and in silico validation.Scientific reports · 2026Article
- When Reality Defies Prediction: Polymorphism, Twinning, and Accordion Crystals.Journal of the American Chemical Society · 2026Article
- Synthesis and characterization of FeCuAlOScientific reports · 2025Article
- Novel Triazole-Carbohydrazide hydrazones with dual antioxidant and antibacterial potential.Scientific reports · 2025Article
- Catalyst-Free Assembly of δ-Lactam-Based Hydrazide-Hydrazone Compounds from 3-Arylglutaconic Anhydrides and Aldazines.International journal of molecular sciences · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
The increase in drug resistance and the high toxicity of current drugs have inspired the scientific community to develop new drugs for various diseases. Hydrazides have become an attractive functional group to easily obtain a plethora of novel compounds with a broad range of biological activities. This review, which contains studies in the literature from the previous five years, focuses on the synthesis methods and biological applications of hydrazides and their derivatives. Here, the details of the experimental reaction conditions used for the synthesis of hydrazides and their derivatives (hydrazide-hydrazones and heterocycle derivatives) are presented, as well as the purification methods and the biological activity of the synthesized compounds.
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Registered trials
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