Evidence map›Paper›PMID 40649258›Full record

ArticleMolecules (Basel, Switzerland)2025

Flavonoid Glycosides and Phenolic Acids from Inula Oculus-Christi Modulate Membrane Organization and Provide Antioxidant Protection.

Ralitsa Veleva, Tanya Topouzova-Hristova, Aneliya Kostadinova, Dayana Benkova, Antoaneta Trendafilova, Viktoria Ivanova, Veselina Moskova-Doumanova, Kirilka Mladenova, Jordan Doumanov, Vesela Yordanova and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antioxidant Activity and HepG2 Cytoprotection of Water-Soluble Chili Pepper Polyphenols.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Article
  2. Article
  3. Polyphenols fromMembranes · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ralitsa VelevaFaculty of Biology, Sofia University 'St. Kliment Ohridski', 1164 Sofia, Bulgaria.
Tanya Topouzova-HristovaFaculty of Biology, Sofia University 'St. Kliment Ohridski', 1164 Sofia, Bulgaria.ORCID 0000-0002-1575-0790
Aneliya KostadinovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0002-8097-3608
Dayana BenkovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.
Antoaneta TrendafilovaCentre of Competence "Sustainable Utilization of Bio-Resources and Waste of Medicinal and Aromatic Plants for Innovative Bioactive Products" (BIORESOURCES BG), 1000 Sofia, Bulgaria.ORCID 0000-0001-5273-176X
Viktoria IvanovaCentre of Competence "Sustainable Utilization of Bio-Resources and Waste of Medicinal and Aromatic Plants for Innovative Bioactive Products" (BIORESOURCES BG), 1000 Sofia, Bulgaria.ORCID 0009-0007-9056-0333
Veselina Moskova-DoumanovaFaculty of Biology, Sofia University 'St. Kliment Ohridski', 1164 Sofia, Bulgaria.ORCID 0000-0001-5316-5835
Kirilka MladenovaFaculty of Biology, Sofia University 'St. Kliment Ohridski', 1164 Sofia, Bulgaria.
Jordan DoumanovFaculty of Biology, Sofia University 'St. Kliment Ohridski', 1164 Sofia, Bulgaria.
Vesela YordanovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0003-0753-8084
Galya StanevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.

Funding

Program "Research, Innovation and Digitization for Smart Transformation" 2021-2027, co-funded by the EU Centre of Competence "Sustainable Utilization of Bio-resources and Waste of Medicinal and Aromatic Plants for Innovative Bioactive Products" (BIORESOURCES BG), project BG16RFPR002-1.014-0001
6 · The paper itself

Abstract

Oxidative stress induces lipid peroxidation within the membrane bilayer, thereby compromising membrane integrity. Polyphenols (PPs), renowned for their antioxidant properties, have been shown to mitigate oxidative damage. Here, we investigated the structural and antioxidant effects of PPs-specifically flavonoid glycosides (FGs) and phenolic acids (PAs)-extracted from

Indexed as

AntioxidantsCell MembraneFlavonoidsGlycosidesHydroxybenzoatesAnimalsDogsHumansLipid PeroxidationMadin Darby Canine Kidney CellsMembrane FluidityMembrane MicrodomainsOxidative StressPlant ExtractsPolyphenolsAntioxidantsFlavonoidsGlycosidesHydroxybenzoatesphenolic acidPlant ExtractsPolyphenolsA549 cellsflavonoid glycosidesInula oculus-christilipid orderphenolic acidsrafts

Identifiers

PMID40649258
PMCPMC12250669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.