Rapid and Effective Recovery of Oleanolic and Maslinic Acids from Olive Leaves Using SFE and pH-Zone Centrifugal Partition Chromatography.

Lemonia Antoniadi, Apostolis Angelis, Theodora Nikou, Dimitris Michailidis, Leandros A Skaltsounis

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

Influence of Ultrasound-Assisted and Supercritical COMolecules (Basel, Switzerland) · 2026
Article

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Lemonia AntoniadiPharmaGnose S.A., 57th km Athens-Lamia National Road, 32011 Oinofyta, Greece.ORCID 0000-0002-9913-2913

Apostolis AngelisDivision of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece.ORCID 0000-0002-5100-0321

Theodora NikouDivision of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece.ORCID 0000-0001-5810-8602

Dimitris MichailidisPharmaGnose S.A., 57th km Athens-Lamia National Road, 32011 Oinofyta, Greece.ORCID 0000-0002-3264-6186

Leandros A SkaltsounisDivision of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece.

Funding

European Commission 101131346

6 · The paper itself

Abstract

Olive leaves, the main byproducts of olive cultivation, are characterized by a plethora of bioactive metabolites with significant nutritional value. Their main pentacyclic triterpenes, Oleanolic Acid (OA) and Maslinic Acid (MA), are two high added-value compounds with remarkable activities. This study aimed to develop an efficient methodology for extracting and purifying OA and MA, utilizing Supercritical Fluid Extraction (SFE) and Centrifugal Partition Chromatography (CPC)-two modern, scalable, and green techniques. A total of 21 g of olive leaves were subjected to SFE using supercritical CO

Indexed as

Chromatography, Supercritical FluidOleaOleanolic AcidPlant LeavesTriterpenesCentrifugationHydrogen-Ion ConcentrationPlant Extractsmaslinic acidOleanolic AcidPlant ExtractsTriterpenesco-solventenzymatic activitymaslinic acidoleanolic acidpH-zone refining CPCSFE

Identifiers

PMID40649228

DOI10.3390/molecules30132709

PMCPMC12250858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.