Synthesis of Azide-Labeled β-Lactosylceramide Analogs Containing Different Lipid Chains as Useful Glycosphingolipid Probes.

Basant Mohamed, Rajendra Rohokale, Xin Yan, Amany M Ghanim, Nermine A Osman, Hanan A Abdel-Fattah, Zhongwu Guo

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Contemporary Synthetic Glycoscience: A Theme Issue Dedicated to the Memory of Hans Paulsen.Molecules (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Basant MohamedDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.

Rajendra RohokaleDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0001-8083-0466

Xin YanDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-1846-3241

Amany M GhanimDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.

Nermine A OsmanDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.ORCID 0009-0009-0455-6982

Hanan A Abdel-FattahDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.

Zhongwu GuoDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.

Funding

NIH HHS 1R21AI170129-02

6 · The paper itself

Abstract

β-Lactosylceramide (β-LacCer) is not only a key intermediate in the biosynthesis of complex glycosphingolipids (GSLs) but also an important regulator of many biological processes. To facilitate the investigation of β-LacCer and other GSLs, a series of β-LacCer analogs with an azido group at the 6-

Indexed as

AzidesGlycosphingolipidsLactosylceramidesLipidsMolecular ProbesClick ChemistryMolecular StructureAzidesGlycosphingolipidsLactosylceramidesLipidsMolecular Probesazidecarbohydratesglycolipidsglycosphingolipidslactoselipidssynthesisβ-Lactosylceramide

Identifiers

PMID40649186

DOI10.3390/molecules30132667

PMCPMC12251015

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