Evidence map›Paper›PMID 40648907›Full record

ArticleJournal of clinical medicine2025

Pain Relief, Disability, and Hospital Costs After Intradiscal Ozone Treatment or Microdiscectomy for Lumbar Disc Herniation: A 24-Month Real-World Prospective Study.

Sara Bisshopp, Renata Linertová, Miguel A Caramés, Adam Szolna, Ignacio J Jorge, Minerva Navarro, Brian Melchiorsen, Benjamín Rodríguez-Díaz, Jesús M González-Martín, Bernardino Clavo

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07325851 (Prospective and Observational Study of Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029. Prospective Study EPOOzo-2.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07325851 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective and Observational Study of Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029. Prospective Study EPOOzo-2.

Typeobservational_patient_registrySponsorBernardino Clavo, MD, PhDRan2026 to 2030Enrolled120ConditionsChemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity, Chronic Pain, Delayed Wound HealingArmsOzone Therapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara BisshoppNeurosurgery, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Renata LinertováFundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), 35019 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-0138-9252
Miguel A CaramésChronic Pain Unit, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Adam SzolnaNeurosurgery, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Ignacio J JorgeChronic Pain Unit, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Minerva NavarroChronic Pain Unit, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Brian MelchiorsenNeurosurgery, Dr. Negrín University Hospital, 35019 Las Palmas, Spain.
Benjamín Rodríguez-DíazFundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), 35019 Las Palmas de Gran Canaria, Spain.
Jesús M González-MartínFundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), 35019 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-6816-4157
Bernardino ClavoFundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), 35019 Las Palmas de Gran Canaria, Spain.ORCID 0000-0003-2522-1064

Funding

Cabildo de Gran Canaria (Las Palmas, Spain) CIGC'2023-24Colegio Oficial de Médicos de Las Palmas (Las Palmas, Spain) I19/18Instituto de Salud Carlos III PI17/00120
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

costsdiscectomy or microdiscectomydisc herniationintradiscal ozone therapylumbar painradicular pain

Identifiers

PMID40648907
PMCPMC12250310

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.