Evidence map›Paper›PMID 40648703›Full record

ReviewNanomaterials (Basel, Switzerland)2025

Biomimetic Cellulose Nanocrystals Composite Hydrogels: Recent Progress in Surface Modification and Smart Soft Actuator Applications.

Yuzhu Cui, Zekai Wang, Mingliang Zhao, Zhihui Wang, Lu Zong

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuzhu CuiKey Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics, Qingdao University of Science & Technology, Qingdao 266042, China.
Zekai WangKey Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics, Qingdao University of Science & Technology, Qingdao 266042, China.
Mingliang ZhaoKey Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics, Qingdao University of Science & Technology, Qingdao 266042, China.
Zhihui WangKey Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics, Qingdao University of Science & Technology, Qingdao 266042, China.
Lu ZongKey Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics, Qingdao University of Science & Technology, Qingdao 266042, China.ORCID 0000-0002-2108-2063

Funding

China Postdoctoral Science Foundation No. 2023M732976National Natural Science Foundation of China No. 51903134Natural Science Foundation of Shandong Province No. ZR2024QB049Youth Innovation Team Project of Shandong Province, China No. 2023KJ311
6 · The paper itself

Abstract

Cellulose nanocrystals (CNCs), derived from renewable biomass, have emerged as a pivotal component in the design of biomimetic composite hydrogels due to their exceptional mechanical strength, biocompatibility, and tunable surface chemistry. This review comprehensively explores recent advancements in surface modification strategies for CNCs (physical adsorption, chemical grafting, and bio-functionalization) and their impacts on the structure and properties of hydrogel networks, with particular emphasis on mechanical properties. Future applications in light/thermal/electrical-responsive soft actuators are critically analyzed. Guided by biomimetic design principles, the anisotropic mechanical responses induced by CNC-oriented alignment are explored, along with their cutting-edge advancements in soft robotics, wearable sensing, and biomedical devices. Perspectives are provided on future directions, including multi-stimuli synergistic actuation systems and sensing-actuation integration architectures. This work establishes a fundamental framework for designing CNC-enhanced smart hydrogels with tailored functionalities and hierarchical structures.

Indexed as

biomimeticcellulose nanocrystalshydrogelsmechanical propertiessoft actuatorsurface modification

Identifiers

PMID40648703
PMCPMC12251025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.