Evidence map›Paper›PMID 40648058›Full record

ReviewPlants (Basel, Switzerland)2025

Beyond Single-Pathogen Models: Understanding Mixed Infections Involving Phytoplasmas and Other Plant Pathogens.

Shao-Shuai Yu, Wei Wei

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shao-Shuai YuCoconut Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wenchang 571339, China.ORCID 0000-0001-7575-629X
Wei WeiMolecular Plant Pathology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA.ORCID 0000-0003-3561-913X

Funding

the Fund of Epidemic Monitoring and Prevention of Crop Pests, Diseases, and Rodents of the Ministry of Agriculture and Rural Affairs of China 102125211630150009005the Hainan Provincial Natural Science Foundation of China 323RC524
6 · The paper itself

Abstract

Phytoplasmas are wall-less, phloem-restricted bacteria responsible for numerous significant plant diseases worldwide. An increasing body of evidence indicates that phytoplasmas can coexist with other pathogens in mixed infections, including various 16Sr group phytoplasmas, 'Candidatus Liberibacter' species, viruses, spiroplasmas, fungi, and other difficult-to-culture phloem-limited bacteria. These interactions challenge established views regarding the causes, detection, and management of plant diseases. This review consolidates existing knowledge on the diversity and epidemiology of phytoplasma-related mixed infections, with a particular emphasis on documented co-infections across various host plants and regions, especially in tropical and subtropical areas. Mixed infections affect disease severity, symptom expression, vector behavior, and pathogen dissemination, highlighting the limitations of pathogen-specific diagnostic and control strategies. The necessity for tools to detect multiple pathogens, enhanced understanding of pathogen-pathogen and host-pathogen interactions, and comprehensive surveillance systems is emphasized. Ultimately, breeding for resistance must consider the complexities of natural co-infections to ensure effective protection of crops. Addressing the challenges presented by phytoplasma-related mixed infections is crucial for developing resilient and sustainable plant health strategies in the face of increasing ecological and agricultural pressures.

Indexed as

co-infection‘one pathogen, one disease’ conceptplant disease preventionplant pathobiome paradigmunculturable plant pathogen

Identifiers

PMID40648058
PMCPMC12251814

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.