Evidence map›Paper›PMID 40647486›Full record

ArticleCancers2025

TTF-1 Negativity Predicts Poor Outcomes in Advanced Non-Squamous NSCLC Also in the Immunotherapy Era: A Multicenter Cohort Study and Meta-Analysis.

Leonardo Brunetti, Valentina Santo, Alessandro Galletti, Alain Gelibter, Antonio Lugini, Gian Paolo Spinelli, Daniele Santini, Alessio Cortellini, Alessia Vendittelli, Giuseppina Rita Di Fazio and 11 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Leonardo BrunettiDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Valentina SantoDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Alessandro GallettiDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.ORCID 0000-0001-7444-2993
Alain GelibterDivision of Medical Oncology B, Policlinico Umberto I, 'La Sapienza' University, 00161 Rome, Italy.ORCID 0000-0002-7832-5281
Antonio LuginiDepartment of Oncology, San Giovanni-Addolorata Hospital, 00184 Rome, Italy.
Gian Paolo SpinelliUOC Territorial Oncology, UOS Experimental/IP-SL Latina-CdS, "Sapienza" University of Rome-Polo Pontino, 04011 Aprilia, Italy.ORCID 0000-0002-4363-6274
Daniele SantiniUOC Oncologia A, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Alessio CortelliniDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Alessia VendittelliDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Giuseppina Rita Di FazioDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Fabrizio CitarellaDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.ORCID 0000-0003-3096-4452
Giulia La CavaDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Emanuele Claudio MingoDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.ORCID 0009-0009-2918-7693
Matteo FiorentiDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Leonardo CristofaniDepartment of Oncology, San Giovanni-Addolorata Hospital, 00184 Rome, Italy.
Sabrina MariottiUOSD Oncologia Medica, Policlinico Tor Vergata, 00133 Rome, Italy.
Serena RicciardiDivision of Medical Oncology, San Camillo Forlanini Hospital, 00152 Rome, Italy.ORCID 0000-0001-5401-4836
Francesco PantanoDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Bruno VincenziDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Giuseppe ToniniDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.
Marco RussanoDepartment of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, 200-00128 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

immunotherapyNSCLCPD-L1TTF-1

Identifiers

PMID40647486
PMCPMC12248803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.