ReviewCancers2025
Role of Radiomics to Predict Malignant Transformation of Sinonasal Inverted Papilloma: A Systematic Review.
Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of Radiomics to Predict Disease Recurrence in Sinonasal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026Pooled it
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSinonasal inverted papilloma is a benign but aggressive tumour of the sinonasal tract. It has the potential for malignant transformation into sinonasal squamous cell carcinoma. Radiomics, which involves the extraction and analysis of quantitative imaging features, has emerged as a promising tool in prediction of tumour behaviour. This systematic review aims to critically evaluate the current literature on the application of radiomics in predicting the malignant transformation of sinonasal inverted papilloma.
methodsA comprehensive literature search was conducted across Medline (via PubMed), EMBASE, and Web of Science. Studies investigating the use of radiomics to predict malignant transformation in sinonasal inverted papilloma were selected based on predefined inclusion criteria. Methodological quality and risk of bias were assessed using the QUADAS-2 tool and the Radiomics Quality Score (RQS).
resultsFive studies were included, encompassing 837 participants. All studies were retrospective and utilised MRI-based radiomics in the construction of their models. The radiomic models demonstrated satisfactory predictive performance. The median AUCs across the included studies were 0.954 (range: 0.901-0.987) in the training set and 0.914 (range: 0.8-0.989) in the validation set.
conclusionsThis systematic review highlights the potential of radiomics as a predictive tool for the malignant transformation of sinonasal inverted papilloma. Radiomics shows promise as a non-invasive adjunct for clinical decision-making. However, further research is needed to standardise methodologies and validate these findings in larger multicentre cohorts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.