Evidence map›Paper›PMID 40647461›Full record

ArticleCancers2025

Serum Complement Factor H: A Marker for Progression and Outcome Prediction Towards Immunotherapy in Cutaneous Squamous Cell Carcinoma.

Glenn Geidel, Laura Adam, Sabrina Bänsch, Nathan Fekade, Benjamin Deitert, Alessandra Rünger, Julian Kött, Tim Zell, Isabel Heidrich, Daniel J Smit and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Complement system in cancer: friend or foe of immunotherapy.Journal for immunotherapy of cancer · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Glenn GeidelDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0008-3999-5902
Laura AdamDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Sabrina BänschDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Nathan FekadeDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0008-0315-3201
Benjamin DeitertDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Alessandra RüngerDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-4465-5282
Julian KöttDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-2073-3909
Tim ZellDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0004-8096-7402
Isabel HeidrichDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-6894-1913
Daniel J SmitFleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-3190-9511
Klaus PantelFleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-5736-2772
Stefan W SchneiderDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-4679-7137
Christoffer GebhardtDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-7090-9584

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cemiplimabcomplement factor Hcutaneous squamous cell carcinomaimmunotherapyliquid biopsy

Identifiers

PMID40647461
PMCPMC12249423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.