Evidence map›Paper›PMID 40647415›Full record

ArticleCancers2025

Multimodal Deep Learning for Stage Classification of Head and Neck Cancer Using Masked Autoencoders and Vision Transformers with Attention-Based Fusion.

Anas Turki, Ossama Alshabrawy, Wai Lok Woo

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anas TurkiDepartment of Computer and Information Science, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Ossama AlshabrawyDepartment of Computer and Information Science, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0002-7293-8511
Wai Lok WooDepartment of Computer and Information Science, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0002-8698-7605

Funding

Saudi Arabia, Research and Innovation 1120
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive cancer, and accurate staging using the AJCC system is essential for treatment planning. This study aims to enhance AJCC staging by integrating both clinical and imaging data using a multimodal deep learning pipeline. We propose a framework that employs a VGG16-based masked autoencoder (MAE) for self-supervised visual feature learning, enhanced by attention mechanisms (CBAM and BAM), and fuses image and clinical features using an attention-weighted fusion network. The models, benchmarked on the HNSCC and HN1 datasets, achieved approximately 80% accuracy (four classes) and ~66% accuracy (five classes), with notable AUC improvements, especially under BAM. The integration of clinical features significantly enhances stage-classification performance, setting a precedent for robust multimodal pipelines in radiomics-based oncology applications.

Indexed as

AJCC staginghead and neck cancermasked autoencodermultimodal fusionradiomicsvision transformer

Identifiers

PMID40647415
PMCPMC12248538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.