Evidence map›Paper›PMID 40647365›Full record

ArticleCancers2025

TOPK Drives IL19-Mediated Crosstalk Between Cancer Cells and Fibroblasts to Promote Solar UV-Induced Skin Damage and Carcinogenesis.

Asad U Khan, Qiushi Wang, Eunmiri Roh, Sally E Dickinson, Georg T Wondrak, Clara Curiel-Lewandowski, Ann M Bode, Tianshun Zhang

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asad U KhanThe Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.ORCID 0000-0001-5361-8718
Qiushi WangThe Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.
Eunmiri RohThe Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.ORCID 0000-0003-4385-2046
Sally E DickinsonDepartment of Pharmacology, College of Medicine, University of Arizona Cancer Center, Skin Cancer Institute, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0002-2049-543X
Georg T WondrakDepartment of Pharmacology, College of Medicine, University of Arizona Cancer Center, Skin Cancer Institute, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0003-4799-8608
Clara Curiel-LewandowskiDepartment of Pharmacology, College of Medicine, University of Arizona Cancer Center, Skin Cancer Institute, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0001-8982-6252
Ann M BodeThe Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.ORCID 0000-0002-7432-082X
Tianshun ZhangThe Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.ORCID 0000-0001-7018-8393

Funding

Targeted Prevention for Non-Melanoma Skin CancerP01CA229112 · NCI · UNIVERSITY OF ARIZONA · PI MANSOUR, HEIDI M. · 2019 to 2023
$7.1M
he Hormel Foundaton 001NCI NIH HHS P01 CA229112NIH HHS 1P01CA229112-06
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cSCCfibroblastIL19keratinocytesRNAseqTOPK

Identifiers

PMID40647365
PMCPMC12248498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.