Evidence map›Paper›PMID 40647231›Full record

SynthesisNutrients2025

Evolving Research Focus on Diet and Cardiovascular Disease: A Systematic Review of 298 Cohort Studies Published from 2019 to 2024.

Vicky Wai Ki Chan, Gebretsadkan Gebremedhin Gebretsadik, Pooja Panchal, Noya Yue Zhu, Daniel Kam Wah Mok, Kwok Tai Chui, Kenneth Ka Hei Lo

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vicky Wai Ki ChanDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0009-0001-5676-7417
Gebretsadkan Gebremedhin GebretsadikDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-8437-1751
Pooja PanchalDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-0875-9121
Noya Yue ZhuJockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China.
Daniel Kam Wah MokDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-6677-2949
Kwok Tai ChuiSchool of Science and Technology, Hong Kong Metropolitan University, Hong Kong SAR, China.ORCID 0000-0001-7992-9901
Kenneth Ka Hei LoDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0003-4624-2737

Funding

Start-up Fund for New Recruits BE91
6 · The paper itself

Abstract

BACKGROUND/

objectivesCardiovascular diseases (CVDs) are a leading cause of mortality globally. Growing studies have been conducted to examine the diet-CVD association to alleviate the health and economic burdens associated with CVDs, but beneficial dietary factors may vary by study region and cohort. There was a need to identify the trends in diet-CVD research by study region and current emerging dietary exposures of interest, which could inform areas for future research and the regions where evidence is relatively limited.

methodsA comprehensive search of multiple databases was performed to identify eligible prospective cohorts examining diet-CVD associations published between 2019 and 2024. Trends in dietary exposure, including dietary patterns, food groups, and nutrients, were analyzed by publication year and geographical distribution.

resultsA total of 298 studies were included in the review. While the United States continued to lead in the number of CVD-diet cohort studies, China has significantly increased its contributions over the past five years, increasing from 2.1% to 14.3%. The cohorts that contributed the most to the literature included the Nurses' Health Study and the Danish Diet, Cancer, and Health cohort. Although food groups accounted for the highest number with respect to dietary exposure overall, there was a notable shift in diet-CVD cohort studies from a focus on nutrients to dietary patterns. Plant-based and Mediterranean diets were the most frequently investigated, while ultra-processed foods and country-specific dietary indices also gained prominence.

conclusionsThis systematic review highlighted the shift towards dietary patterns in nutritional epidemiology, emphasizing the importance of understanding the role of nutrition in health through holistic dietary approaches. The observed trends in dietary exposure research suggested the need for future studies to delve deeper into the complexities of dietary patterns, including how cultural and socioeconomic elements defined the nuances of country-specific dietary patterns.

Indexed as

Cardiovascular DiseasesDietCohort StudiesDiet, HealthyHumanscardiovascular diseasescohort studiesdietary exposuresdietary patternsfood groupsnutrientssystematic reviewtrend analysis

Identifiers

PMID40647231
PMCPMC12252054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.