Evidence map›Paper›PMID 40647190›Full record

Trial reportNutrients2025

Role of the Ketogenic Diet Therapy and ACTH as Second Treatments in Drug-Resistant Infantile Epileptic Spasms Syndrome.

Anastasia Dressler, Letizia Bonfanti, Petra Trimmel-Schwahofer, Barbara Porsche, Simona Bertoli, Christoph Male

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anastasia DresslerDepartment of Paediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, ERN EpiCARE, Medical University Vienna, A-1090 Wien, Austria.ORCID 0000-0002-1518-8646
Letizia BonfantiPostgraduate School of Clinical Nutrition, University of Milan, 20122 Milan, Italy.
Petra Trimmel-SchwahoferDepartment of Paediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, ERN EpiCARE, Medical University Vienna, A-1090 Wien, Austria.
Barbara PorscheDepartment of Paediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, ERN EpiCARE, Medical University Vienna, A-1090 Wien, Austria.ORCID 0000-0002-3126-3415
Simona BertoliIRCCS Auxologico Italiano, Research Laboratory on Nutrition and Obesity, 20145 Milan, Italy.ORCID 0000-0001-5867-8074
Christoph MaleDepartment of Paediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, ERN EpiCARE, Medical University Vienna, A-1090 Wien, Austria.ORCID 0000-0002-4989-6421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenocorticotropic HormoneDiet, KetogenicDrug Resistant EpilepsySpasms, InfantileAnticonvulsantsCohort StudiesFemaleHumansInfantMaleTreatment OutcomeAdrenocorticotropic HormoneAnticonvulsantsACTHanti-seizure medicationsinfantile epileptic spasms syndromeketogenic diet therapysecond treatment

Identifiers

PMID40647190
PMCPMC12251253

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.