Evidence map›Paper›PMID 40646784›Full record

ReviewAnimals : an open access journal from MDPI2025

Review: Gut Microbiota-A Powerful Tool for Improving Pig Welfare by Influencing Behavior Through the Gut-Brain Axis.

Xiaoying Jian, Duo Zheng, Shengping Pang, Peiqiang Mu, Jun Jiang, Xu Wang, Xiliang Yan, Yinbao Wu, Yan Wang

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Feeding of Undocked Pigs: Effects of Feed Components and Feed Composition.Animals : an open access journal from MDPI · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoying JianState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0009-0002-3903-9124
Duo ZhengState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Shengping PangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Peiqiang MuCollege of Life Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-0269-9401
Jun JiangCollege of Life Science, South China Agricultural University, Guangzhou 510642, China.
Xu WangInstitute of Quality Standard and Monitoring Technology for Agro-Products of Guangdong Academy of Agricultural Sciences, Guangzhou 510642, China.
Xiliang YanState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-4173-6228
Yinbao WuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Yan WangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.

Funding

Construction Project of Modern Agricultural Science and Technology Innovation Alliance in Guangdong Province 2024CXTD20Department of Agriculture and Rural Affairs of Guangdong Province 2024-WPY-00-012National Key R&D Program of China 2023YFD1301904Science and Technology Program of Guangdong Province grant no. 2023B0202010029
6 · The paper itself

Abstract

Animal welfare is one of the core concerns in the field of animal science, with behavior serving as a direct reflection of emotional state and health, and thus a key indicator for welfare assessment. With the widespread adoption of intensive farming systems, abnormal behaviors in pigs have become a prominent marker of compromised welfare. In the past few years, the role of gut microbes in the regulation of animal behavior has received increasing attention. This review summarizes the strong relationship between pig behavior and welfare, and focuses on the emerging research linking gut microbiota to behavioral expression in pigs. Furthermore, it outlines the mechanisms by which the microbiota modulates behavior through the microbiota-gut-brain axis (MGBA), including immune, endocrine, and neural pathways. Additionally, the potential of microbiota-targeted interventions to improve pig welfare, including probiotics and prebiotics, will be evaluated. As a critical bridge connecting physiology and psychology, the gut microbiota shows significant promise for advancing welfare regulation in pigs.

Indexed as

behaviormicrobiota–gut–brain axispigwelfare

Identifiers

PMID40646784
PMCPMC12248656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.