Evidence map›Paper›PMID 40646660›Full record

ArticleAnatomical sciences education2025

AI's ability to interpret unlabeled anatomy images and supplement educational research as an AI rater.

Lord J Hyeamang, Tejas C Sekhar, Emily Rush, Amy C Beresheim, Colleen M Cheverko, William S Brooks, Abbey C M Breckling, M Nazmul Karim, Christopher Ferrigno, Adam B Wilson

Abstract read
In one paragraph

Article in Anatomical sciences education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lord J HyeamangRush Medical College, Rush University, Chicago, Illinois, USA.
Tejas C SekharRush Medical College, Rush University, Chicago, Illinois, USA.
Emily RushAcademic Affairs, Rush University, Chicago, Illinois, USA.
Amy C BeresheimDepartment of Anatomy and Cell Biology, Rush Medical College, Rush University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1672-1131
Colleen M CheverkoDepartment of Anatomy and Cell Biology, Rush Medical College, Rush University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-9065-1768
William S BrooksDepartment of Medical Education, Marnix E. Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-4745-9295
Abbey C M BrecklingDepartment of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-4322-4744
M Nazmul KarimSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Christopher FerrignoDepartment of Anatomy and Cell Biology, Rush Medical College, Rush University, Chicago, Illinois, USA.
Adam B WilsonDepartment of Anatomy and Cell Biology, Rush Medical College, Rush University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1221-5602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence suggests custom chatbots are superior to commercial generative artificial intelligence (GenAI) systems for text-based anatomy content inquiries. This study evaluates ChatGPT-4o's and Claude 3.5 Sonnet's capabilities to interpret unlabeled anatomical images. Secondarily, ChatGPT o1-preview was evaluated as an AI rater to grade AI-generated outputs using a rubric and was compared against human raters. Anatomical images (five musculoskeletal, five thoracic) representing diverse image-based media (e.g., illustrations, photographs, MRI) were annotated with identification markers (e.g., arrows, circles) and uploaded to each GenAI system for interpretation. Forty-five prompts (i.e., 15 first-order, 15 second-order, and 15 third-order questions) with associated images were submitted to both GenAI systems across two timepoints. Responses were graded by anatomy experts for factual accuracy and superfluity (the presence of excessive wording) on a three-point Likert scale. ChatGPT o1-preview was tested for agreement against human anatomy experts to determine its usefulness as an AI rater. Statistical analyses included inter-rater agreement, hierarchical linear modeling, and test-retest reliability. ChatGPT-4o's factual accuracy score across 45 outputs was 68.0% compared to Claude 3.5 Sonnet's score of 61.5% (p = 0.319). As an AI rater, ChatGPT o1-preview showed moderate to substantial agreement with human raters (Cohen's kappa = 0.545-0.755) for evaluating factual accuracy according to a rubric of textbook answers. Further improvements and evaluations are needed before commercial GenAI systems can be used as credible student resources in anatomy education. Similarly, ChatGPT o1-preview demonstrates promise as an AI assistant for educational research, though further investigation is warranted.

Indexed as

AnatomyArtificial IntelligenceEducational MeasurementHumansObserver VariationReproducibility of ResultsAI in researchanatomy imagesChatGPTClaudegenerative artificial intelligence

Identifiers

PMID40646660
PMCPMC12511656

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.