Observational studyCritical care (London, England)2025
Epidemiology, outcomes, and factors associated with mortality in pediatric acute respiratory distress syndrome in hospitalized Thai children: a nationwide retrospective analysis, 2015-2022.
Observational study in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Independent predictors of long-term pulmonary function recovery in patients with acute respiratory distress syndrome: a meta-analysis.American journal of translational research · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPediatric acute respiratory distress syndrome (PARDS) causes significant morbidity and mortality, especially in resource-limited settings. This study assessed national hospital and PICU admission rates, regional disparities, and factors associated with mortality in Thai children with PARDS.
methodsA nationwide retrospective study was conducted using National Health Security Office (NHSO) data from 2015 to 2022. Children aged 1 month to < 18 years with a diagnosis of PARDS (ICD-10-TM code J80) were included. Multivariable logistic regression was used to identify factors associated with mortality, reported as adjusted relative risk (ARR) with 95% confidence intervals (CI).
resultsAmong 4,241 patients, the prevalence of PARDS ranged from 29.8 to 37.2 per 100,000 hospital admissions, while PICU admission rates ranged from 13.5 to 18.6 per 1,000. Bangkok had the highest rate in 2022 (27.0 per 1,000) but the lowest mortality at 25.6%. The overall mortality rate declined from 53.7% in 2015 to 37.7% in 2022 but remained high in resource-limited regions. Malignancy (ARR 1.29, 95% CI 1.17-1.43 p < 0.001), drowning (ARR 1.43, 95% CI 1.29-1.60, p < 0.001), sepsis and septic shock (ARR 1.19, 95% CI 1.12-1.27, p < 0.001), non-major pulmonary trauma (ARR 1.43, 95% CI 1.16-1.77, p = 0.001), and cardiovascular dysfunction (ARR 1.41, 95% CI 1.32-1.51, p < 0.001) were strongly associated with mortality. Intubation was significantly associated with increased mortality (ARR 2.52, 95% CI 2.12-3.00, p < 0.001), whereas extracorporeal life support was associated with lower mortality (ARR 0.46, 95% CI 0.35-0.61, p < 0.001).
conclusionsPARDS remains a substantial burden in Thailand, with marked regional differences in access to critical care. Efforts to strengthen healthcare infrastructure and early respiratory support are needed to reduce preventable deaths.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.