Evidence map›Paper›PMID 40646534›Full record

ArticleBMC medical ethics2025

Oncologists' knowledge, practices and ethical opinions about therapeutic misconception: a French national survey.

Thibaud Haaser, S Clair, S Marty, D Berdai, H Hoarau, M C Saux, D Dreyfuss, P J Maternowski

Abstract read
In one paragraph

Article in BMC medical ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Therapeutic Misconception as a Problem of Nonmaleficence by Way of False Hope.Health care analysis : HCA : journal of health philosophy and policy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thibaud HaaserHealth and Research Ethics Centre of Bordeaux, Bordeaux, France. thibaud.haaser@chu-bordeaux.fr.
S ClairHealth and Research Ethics Centre of Bordeaux, Bordeaux, France.
S MartyHealth and Research Ethics Centre of Bordeaux, Bordeaux, France.
D BerdaiHealth and Research Ethics Centre of Bordeaux, Bordeaux, France.
H HoarauHealth and Research Ethics Centre of Bordeaux, Bordeaux, France.
M C SauxHealth and Research Ethics Centre of Bordeaux, Bordeaux, France.
D DreyfussHôpital Tenon, Common and Rare Kidney Diseases, INSERM, UMR-S 1155, Sorbonne University, Paris, France.
P J MaternowskiUniversity Hospital Centre of Bordeaux, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTherapeutic misconception (TM) among research participants refers to the conflation of research goals (generating generalisable knowledge) with clinical care goals (making the best decisions for the participants). Considering the high volume of oncology research, oncologists frequently encounter TM.

aimTo evaluate the knowledge, practices, and ethical concerns of French oncologists regarding TM. MATERIALS AND

methodsA questionnaire was developed to assess oncologists' knowledge and practices concerning TM, then utilised in a national survey of French oncologists from 1 June to 14 July 2023. A descriptive statistical analysis of the responses (according to a Likert scale) was carried out.

resultsIn total, 288 oncologists from various specialties responded to the survey. Initial knowledge of TM was low (16%), but after the definition was provided, 84% reported having encountered TM. Respondents indicated that they paid attention to the information given during participant inclusion; however, approximately half (46%) actively investigated the presence of TM, and 22% admitted to having encouraged TM at least occasionally. Attention to TM significantly declined over the course of study protocols. Awareness of TM, along with ethics education or participation in a research ethics committee, were identified as significant factors influencing responses. The acceptability of TM was nuanced, particularly in protocols recommended to patients receiving last-line treatments. Although 64% of respondents acknowledged a link between TM and dual roles as both investigator and physician, 78% opposed transferring investigative responsibilities to a non-referent oncologist.

conclusionTM is a widespread but still mostly unknown phenomenon which could easily be tackled for better outcomes for patients. This study revealed considerable variability in knowledge, practices, and ethical considerations related to TM among French oncologists. Enhanced education and ethical support are needed to improve awareness and foster appropriate behaviours concerning TM. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticeMedical OncologyOncologistsPractice Patterns, Physicians'Therapeutic MisconceptionAdultFemaleFranceHumansMaleMiddle AgedSurveys and QuestionnairesOncologyPhysicians’ perspectivesResearch ethicsTherapeutic misconception

Identifiers

PMID40646534
PMCPMC12247256

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.