SynthesisBMC complementary medicine and therapies2025
Ginseng supplementation and vascular function: a systematic review and meta-analysis of clinical trials.
Synthesis in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Navigating the Effects of Anti-Atherosclerotic Supplements and Acknowledging Associated Bleeding Risks.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGinseng is a source of pharmacologically active compounds with cardioprotective properties. The aim of the current systematic review and meta-analysis was to investigate the effect of ginseng on vascular function.
methodsElectronic databases, including PubMed, ISI Web of Science, Scopus, and Google Scholar were searched using relevant keywords from inception until February 2025. The eligibility criteria for a full-text review of papers consisted of clinical trials involving subjects aged ≥ 15 years who consumed ginseng and evaluated at least one of the cardiac function markers: flow-mediated dilation (FMD), pulse wave velocity (PWV), augmentation index (AIx), and circulating biomarkers of vascular function.
resultsFrom a total of 328 initial search records, 13 randomized controlled trials were included in the study. Pooled analysis showed a significant increase in FMD level (effect size: 5, SMD: 0.571%, 95% CI: 0.198, 0.943, P = 0.003), and endothelium-derived nitric oxide levels (effect size: 4, SMD: 0.30, 95% CI: 0.01, 0.59, P = 0.045) as well as a significant decrease in PWV (effect size: 7, SMD: ‒0.29 cm/s, 95% CI: ‒0.51, ‒0.06, P = 0.014). No significant effect was observed in AIx (effect size: 9, SMD: ‒0.53%, 95% CI: ‒1.08, 0.03, P = 0.063) following ginseng intake.
conclusionsThe overall results revealed beneficial effects of ginseng on endothelial function and arterial stiffness, as measured by PWV, while it did not change AIx. Further studies are recommended to investigate the effects of ginseng on vascular function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.