ArticleClinical rheumatology2025
Clinical features and risk factors of abdominal IgA vasculitis in adults.
Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- IgA-Associated Vasculitis Presenting With Acute Abdominal Syndrome in an Older Patient.The American journal of case reports · 2026Article
- Atypical presentation of immunoglobulin A vasculitis mimicking acute appendicitis in a pediatric patient: a case report.Future science OA · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundAdult-onset abdominal IgA vasculitis (A-IgAV) presents with abdominal pain as the initial symptom, which is a relatively rare condition that is frequently misdiagnosed.
methodsThis retrospective study utilized clinical data from 125 adult patients diagnosed with IgA vasculitis (IgAV), retrieved from the electronic medical records of the First College of Clinical Medical Science, China Three Gorges University. The study comprehensively investigated the clinical manifestations, evaluated the diagnostic significance of various laboratory markers, and identified features from abdominal CT and endoscopy.
resultsOf the 125 cases analyzed, 42 involved gastrointestinal (GI) complications, while the remaining 83 did not. A-IgAV predominantly affected younger male patients, with a median age of 37, whereas non-abdominal IgA vasculitis (NA-IgAV) was more common in middle-aged women, with a median age of 47. Patients with purpuric lesions affecting two or more areas of the body were statistically more likely to develop GI complications. Elevated white blood cell (WBC) and C-reactive protein/albumin ratio (CAR) levels, along with reduced immunoglobulin M (IgM), were found to be strong predictors of GI complications, offering substantial prognostic value when WBC exceeded 10.340 × 10
conclusionsThe duodenum is the most frequently affected site, followed by the ileum and jejunum. Multi-regional purpura, leukocytosis, or elevated CAR are independent risk factors for GI involvement. Key Points • The duodenum is the most predominantly involved site, followed by the ileum and jejunum. • Purpura affecting two or more regions significantly increased the likelihood of GI involvement. • WBC and CAR were identifed as risk factors, while IgM was identified as a protective factor.
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