Evidence map›Paper›PMID 40646291›Full record

ArticleArchives of osteoporosis2025

Comorbidity burden, management, and in-hospital outcomes in centenarians with proximal hip fracture: a nationwide cohort study (2004-2020).

Juan Carlos Piñeiro-Fernández, Ramón Rabuñal-Rey, Eva Romay-Lema, David Rubal-Bran, Cristina Pedrosa-Fraga, Ana María Santos-Martínez, Yoana Besteiro-Balado, Roi Suárez-Gil, Sonia Pértega-Díaz

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Article in Archives of osteoporosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juan Carlos Piñeiro-FernándezInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain. juan.carlos.pineiro.fernandez@udc.es.
Ramón Rabuñal-ReyInfectious Diseases Unit, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Eva Romay-LemaInfectious Diseases Unit, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
David Rubal-BranInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Cristina Pedrosa-FragaInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Ana María Santos-MartínezInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Yoana Besteiro-BaladoInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Roi Suárez-GilInternal Medicine Department, Lucus Augusti University Hospital, SERGAS, 1 Ulises Romero Street, 27003, Lugo, Spain.
Sonia Pértega-DíazDepartment of Health Sciences, Faculty of Nursing and Podiatry, Universidade da Coruña, Rheumatology and Health Research Group, 15403, Ferrol, Esteiro, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study analyses comorbidity, surgical management, and complications and their impact on in-hospital outcomes in centenarian hip fracture patients admitted in Spain, 2004-2020. It provides evidence on the prognostic impact of comorbidity and in-hospital complications and highlights the need for specific interventions to improve care in this vulnerable population. PURPOSE: This work aims to describe the clinical characteristics, in-hospital progress, and risk factors for worse in-hospital outcomes in centenarian patients with proximal hip fracture (PHF).

methodsA retrospective nationwide cohort study was conducted that included all centenarian patients hospitalized for PHF (2004-2020) according to the Spanish National Health System's Minimum Basic Data Set. Demographic, clinical, and hospitalization-related variables were analyzed. Univariate and multivariate analyses were performed.

resultsThis study included 4261 patients (83.3% women). The mean Charlson comorbidity index (CCI) was 0.9 ± 1.2; 11.4% had severe comorbidity. Surgery was performed in 87.2% of patients and in 44.5% after 48 h of admission. Higher CCI scores (OR 1.3, 95% CI 1.0-1.7) and admission to medical departments (OR 4.11, 95% CI 3.0-5.6) were associated with nonsurgical management. Surgical delays ≥ 48 h were associated with admissions on Saturdays (OR 1.9, 95% CI 1.3-2.8) or to medical departments (OR 2.79, 95% CI 1.34-5.83) and with the development of ≥ 3 complications (OR 1.5, 95% CI 1.1-2.0). Overall, 15% of patients died during hospitalization, with significantly higher mortality in nonsurgical patients (31.8% vs. 12.5%, p < 0.001). In surgical patients, mortality and prolonged hospital stays were primarily related to higher CCI scores and complications.

conclusionsCentenarians with PHF have a low severe disease burden but high in-hospital mortality risk. Key predictors of mortality in surgical patients include higher CCI scores and in-hospital complications. This highlights the relevance of integrated care and early optimization of clinical status. Prospective studies with long-term follow-up are needed to better characterize prognostic factors.

Indexed as

Hip FracturesAged, 80 and overComorbidityFemaleHospitalizationHospital MortalityHumansMalePostoperative ComplicationsRetrospective StudiesRisk FactorsSpainTreatment OutcomeCentenariansComorbidityElectronic health recordsHip fracturesMortalityPatient outcome assessment

Identifiers

PMID40646291
PMCPMC12254154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.