Evidence map›Paper›PMID 40646247›Full record

ArticleScientific reports2025

Spatiotemporal analysis of environmental factors associated with visceral leishmaniasis in northeastern Brazil, 2007-2022.

Quezia Machado Dos Santos Araújo, José Rodrigo Santos Silva, Cláudia Csekö Nolasco de Carvalho, Pedro Dantas Lima, Audrey Rouse Soares Tavares Silva, Sona Jain, Filipe Dantas-Torres, Evander de Jesus Oliveira Batista, Israel Gomes de Amorim Santos, Silvio Santana Dolabella

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Quezia Machado Dos Santos AraújoGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
José Rodrigo Santos SilvaGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Cláudia Csekö Nolasco de CarvalhoDepartment of Animal Science, State University of Alagoas, Santana do Ipanema, AL, Brazil.
Pedro Dantas LimaGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Audrey Rouse Soares Tavares SilvaGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Sona JainGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Filipe Dantas-TorresAggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife, PE, Brazil.
Evander de Jesus Oliveira BatistaLaboratory of Protozoology, Tropical Medicine Nucleus, Federal University of Pará, Belém, Brazil. evander@ufpa.br.
Israel Gomes de Amorim SantosGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Silvio Santana DolabellaGraduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, SE, Brazil. dolabellaufs@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL), caused by the protozoan Leishmania infantum and transmitted by infected female sand flies, remains a significant public health concern in Brazil. This study investigates the clinical and epidemiological profile of VL, including its spatial distribution, temporal trends, and relationship with environmental factors - specifically sanitation, waste collection, and deforestation - in the northeastern region of Brazil from 2007 to 2022. Utilizing data from SINAN, IBGE, and MapBiomas, we observed a higher incidence of VL among males, children under ten years old, and indigenous populations, particularly in the states of Maranhão, Piauí, Bahia, and Ceará. Although a notable decreasing trend in VL cases was observed, the disease remains endemic in these areas. This research identified a positive correlation between VL incidence and environmental factors, such as inadequate sewage systems, insufficient waste collection, and deforestation. These findings suggest that improving urban infrastructure, adopting sustainable land-use practices, and enhancing epidemiological surveillance could help reduce VL incidence in northeastern Brazil.

Indexed as

Leishmaniasis, VisceralAdolescentAdultAnimalsBrazilChildChild, PreschoolEnvironmentFemaleHumansIncidenceInfantLeishmania infantumMaleSanitationSpatio-Temporal AnalysisEnvironmental factorsEpidemiological trendsLeishmania infantumPublic health policySpatial analysis

Identifiers

PMID40646247
PMCPMC12254364

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.