Evidence map›Paper›PMID 40645705›Full record

ArticleJACC. Case reports2025

Double-Outlet Right Ventricle in an Adult With a Univentricular Heart and Total Situs Inversus.

Vincenzo Arenas-Fabbri, Elias Noel Andrade-Cuellar, Saúl Yair Guillot-Castillo, Maria Alejandra Monroy-Jiménez, Andrea Paulina Maldonado-Tenesaca, Rocio Aceves-Millan, Juan Carlos Solis-Gómez, Rogelio Robledo-Nolasco, Diego de Jesús Encinos-Méndez, Ivan Alejandro Elizalde-Uribe

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vincenzo Arenas-FabbriDepartment of Cardiovascular Imaging, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Elias Noel Andrade-CuellarClinical Cardiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico; Cardiac Electrophysiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico. Electronic address: elias.noel.ac@gmail.com.
Saúl Yair Guillot-CastilloClinical Cardiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Maria Alejandra Monroy-JiménezClinical Cardiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Andrea Paulina Maldonado-TenesacaEchocardiography Laboratory, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Rocio Aceves-MillanEchocardiography Laboratory, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Juan Carlos Solis-GómezCardiac Electrophysiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Rogelio Robledo-NolascoCardiac Electrophysiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Diego de Jesús Encinos-MéndezClinical Cardiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.
Ivan Alejandro Elizalde-UribeClinical Cardiology, National Medical Center "November 20th," Institute of Social Security and Services for State Workers, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDouble-outlet right ventricle is a complex conotruncal anomaly in which both great arteries arise predominantly from the right ventricle. The coexistence of total situs inversus and univentricular physiology is exceedingly rare. CASE SUMMARY: A 38-year-old man presented with severe chronic cyanosis (baseline oxygen saturation 65%), NYHA functional class III dyspnea, and right-sided heart failure. Multimodal imaging (echocardiography, CT, and cardiac magnetic resonance) confirmed total situs inversus, a markedly hypoplastic left ventricle anatomically isolated by a muscular ridge, and double-outlet right ventricle with moderate subpulmonary stenosis. His condition was stabilized medically, but surgical risk was deemed prohibitive owing to his univentricular physiology. DISCUSSION: This case underscores the critical importance of comprehensive imaging for delineating complex intracardiac anatomy and illustrates how moderate subpulmonary stenosis can temper pulmonary overcirculation, thereby prolonging survival. TAKE-HOME MESSAGE: Meticulous anatomical definition is essential for managing rare adult congenital heart disease.

Indexed as

cardiac surgerydouble-outlet right ventriclemultimodal imagingnoncommitted ventricular septal defectpostoperative complicationssitus inversusuniventricular heart

Identifiers

PMID40645705
PMCPMC12441456

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.