Evidence map›Paper›PMID 40645701›Full record

ArticleJACC. Case reports2025

Rare Presentation of a Primary Cardiac Mass: Insights Into Multimodal Imaging, Histopathology, and Surgical Management.

Ashraf Samhan, Sowda Ahmed, Alana A Lewis, Paul C Cremer, Lamis ElHarake, Jon W Lomasney, Douglas R Johnston, Mohamed Al-Kazaz

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashraf SamhanFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. Electronic address: ashraf.samhan@nm.org.
Sowda AhmedFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Alana A LewisFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Cardiology, Bluhm Cardiovascular Institute, Chicago, Illinois, USA.
Paul C CremerFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Cardiology, Bluhm Cardiovascular Institute, Chicago, Illinois, USA; Division of Radiology, Northwestern Memorial Hospital, Chicago, Illinois, USA.
Lamis ElHarakeDivision of Cardiology, Bluhm Cardiovascular Institute, Chicago, Illinois, USA.
Jon W LomasneyFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Pathology, Northwestern Memorial Hospital, Chicago, Illinois, USA; Division of Pharmacology, Northwestern Memorial Hospital, Chicago, Illinois, USA.
Douglas R JohnstonFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Cardiac Surgery, Bluhm Cardiovascular Institute, Chicago, Illinois, USA.
Mohamed Al-KazazFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Cardiology, Bluhm Cardiovascular Institute, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cardiac tumors are exceedingly rare, with cardiac hemangiomas constituting 1% to 3% of benign cardiac tumors, making diagnosis and management challenging. A 49-year-old female presented with progressive chest tightness over several years. Multimodal imaging revealed a large cardiac mass within the pericardial space, encasing the left anterior descending artery. Following an inconclusive tissue sampling attempt, surgical resection was performed to guide therapy. Histopathology confirmed cardiac cavernous hemangioma. Multimodal imaging is crucial for characterizing cardiac masses and guiding biopsy and treatment strategies (eg, surgical for sarcoma if feasible versus nonsurgical for lymphoma). Cardiac hemangiomas often present with nonspecific symptoms. Surgical resection remains the definitive treatment, providing symptom relief and histopathologic confirmation.

Indexed as

computed tomographyimagingmagnetic resonance sequencespericardial effusionpositron emission tomographyright ventricletamponadethoracotomy

Identifiers

PMID40645701
PMCPMC12441438

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.