Evidence map›Paper›PMID 40645692›Full record

ArticleJACC. Case reports2025

Use of a Focal Pulsed Field Ablation Catheter to Target Premature Ventricular Contractions From the Papillary Muscle.

Maryam Saleem, Chengyue Jin, Yury Malyshev, Abhishek Maan, Daniel R Musikantow, Vivek Y Reddy

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Ventricular pulsed field ablation from bench to bedside: preclinical and clinical evidence from a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
  2. Concurrent SVT and atrial fibrillation ablation using a dual-energy linear ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryam SaleemHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Chengyue JinHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Yury MalyshevHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Abhishek MaanHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Daniel R MusikantowHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Vivek Y ReddyHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: vivek.reddy@mountsinai.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The papillary muscles are a common site of origin for premature ventricular contractions (PVCs). Radiofrequency ablation of these PVCs is often challenging due to catheter instability and the inability to penetrate fibrotic tissue, leading to limited clinical success in PVC suppression. In this report, we describe the use of pulsed field ablation (PFA), delivered via a novel focal ablation catheter, to successfully treat papillary muscle PVCs in 2 symptomatic, treatment-refractory patients. Both patients had previously undergone at least 1 failed ablation attempt using conventional radiofrequency catheters but achieved durable suppression or reduction in PVC burden after a limited number of PFA applications. Neither patient experienced complications related to the delivery of PFA energy. Although the safety and efficacy of PFA within the ventricle are still being explored, its rapid energy delivery and ability to penetrate fibrotic tissue may make it uniquely suited for ablation of PVCs originating from papillary muscles.

Indexed as

papillary musclespremature ventricular contractionspulsed field ablation

Identifiers

PMID40645692
PMCPMC12441414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.