Evidence map›Paper›PMID 40645686›Full record

ArticleJACC. Case reports2025

The Pivotal Role of Cardiac Magnetic Resonance Imaging in Diagnosing Chronic Chagas Cardiomyopathy.

Syed H Ali, Umer N Khan, Nihar Chandupatla, Youssef Abdullah, Mohammed Mahmoud, Anwar Merie, Aditya Desai, Haritha Saikumar, Kamran Shaikh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Syed H AliInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA. Electronic address: syed.ali@austin.utexas.edu.
Umer N KhanInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Nihar ChandupatlaInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Youssef AbdullahInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Mohammed MahmoudInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Anwar MerieInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Aditya DesaiInternal Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Haritha SaikumarPulmonary Critical Care Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.
Kamran ShaikhCardiovascular Medicine, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Chagas cardiomyopathy (CCM) is a progressive condition marked by myocardial fibrosis, which heightens the risk of severe ventricular arrhythmias (eg, ventricular fibrillation, ventricular tachycardia). Prompt recognition and intervention are particularly crucial in nonendemic regions where CCM often goes underdiagnosed. Here, we discuss 2 cases of Hispanic patients without prior Chagas disease history, each presenting with ventricular fibrillation cardiac arrest and sustained ventricular tachycardia, respectively. Cardiac magnetic resonance was instrumental in diagnosing significant myocardial fibrosis and scarring indicative of CCM. Both patients received automatic implantable cardioverter-defibrillators for secondary prevention of sudden cardiac death, alongside guideline-directed medical therapy, leading to notable clinical improvement. These cases underscore the vital role of cardiac magnetic resonance in detecting myocardial fibrosis and guiding therapy for high-risk patients, illustrating how increased awareness and advanced imaging can enable timely diagnosis and potentially lifesaving treatments in nonendemic areas.

Indexed as

cardiac magnetic resonance imagingcardiomyopathyventricular fibrillationventricular tachycardia

Identifiers

PMID40645686
PMCPMC12441435

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.