Thrombus in Transit Through Patent Foramen Ovale Causing Splenic Infarction.

Rana Rashwan, Judy Rizk, Ingy Etman, Anhar Zokailah, Zeyad Kholeif

Abstract read

In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Patent Foramen Ovale: Epidemiology, Risk Factors, Pathophysiology, Clinical Features, Diagnosis, and Management.MedComm · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rana RashwanCardiovascular Department, Mayo Clinic, Rochester, Minnesota, USA; Alexandria Main University Hospital, Alexandria, Egypt. Electronic address: ranarashwan9@gmail.com.

Judy RizkAlexandria Main University Hospital, Alexandria, Egypt.

Ingy EtmanAlexandria Main University Hospital, Alexandria, Egypt.

Anhar ZokailahAlexandria Main University Hospital, Alexandria, Egypt.

Zeyad KholeifCardiovascular Department, Mayo Clinic, Rochester, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatent foramen ovale (PFO) is often asymptomatic but can cause paradoxical embolism. Although cryptogenic stroke is common, this case is unique due to splenic infarction and a visible thrombus in transit. CASE SUMMARY: A 30-year-old woman presented with acute dyspnea, hemoptysis, and left upper quadrant abdominal pain. Investigations revealed deep vein thrombosis complicated by pulmonary embolism and paradoxical embolization through PFO, leading to splenic infarction-a rare sequence of events.

conclusionsScreening for PFO should be considered in patients with venous thrombosis and cryptogenic embolism. Thrombus in transit through PFO presents a challenge due to the lack of consensus on management.

Indexed as

case reportparadoxical embolizationpatent foramen ovalepulmonary embolismsplenic infarctionsystemic embolizationthrombus in transit

Identifiers

PMID40645685

DOI10.1016/j.jaccas.2025.103924

PMCPMC12441429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.