Evidence map›Paper›PMID 40645631›Full record

ArticleBMJ open2025

Effects of acupuncture on pregnancy outcomes in infertile women with polycystic ovarian syndrome: a protocol for systematic review and meta-analysis.

Jiashan Li, Tian Hang, Xiaoyan Wang, Huanfang Xu, Yigong Fang

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiashan LiChina Academy of Chinese Medical Sciences Institute of Acupuncture and Moxibustion, Beijing, China.ORCID http://orcid.org/0000-0002-6567-6402
Tian HangChina Academy of Chinese Medical Sciences Institute of Acupuncture and Moxibustion, Beijing, China.ORCID http://orcid.org/0000-0003-3413-6822
Xiaoyan WangChina Academy of Chinese Medical Sciences Institute of Acupuncture and Moxibustion, Beijing, China.ORCID http://orcid.org/0009-0000-1665-2431
Huanfang XuChina Academy of Chinese Medical Sciences Institute of Acupuncture and Moxibustion, Beijing, China fangyigong@163.com huanfang_xu@126.com.ORCID http://orcid.org/0000-0002-0005-5648
Yigong FangChina Academy of Chinese Medical Sciences Institute of Acupuncture and Moxibustion, Beijing, China fangyigong@163.com huanfang_xu@126.com.ORCID http://orcid.org/0000-0001-7879-2843

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolycystic ovarian syndrome (PCOS) is a common endocrine disorder that affects reproductive-age women, impairing their ability to conceive and sustain fertility. The efficacy of conventional therapies varies among individuals and is often accompanied by multiple side effects. Acupuncture has shown potential in fertility management for PCOS patients. However, the current evidence on its impact on pregnancy outcomes remains inconclusive. This study aims to synthesise the latest evidence regarding the efficacy and safety of acupuncture in infertile women with PCOS. METHODS AND ANALYSIS: A comprehensive literature review will be conducted by searching for randomised controlled trials of acupuncture for infertile women with PCOS in English and Chinese language databases, including the Cochrane Database of Clinical Trials, PubMed, EMBASE, CNKI, Wanfang, VIP and SinoMed. The primary outcome will be live birth rat (LBR) and clinical pregnancy rate (CRP). The secondary outcomes will include multiple pregnancy rate (MPR), ongoing pregnancy rate (OPR), miscarriage rate (MR), ovulation rate (OR), hyperstimulation ovarian syndrome (OHSS) and adverse events. The risk of bias will be assessed using the Cochrane Risk of Bias 2.0 tool. Meta-analysis will be conducted to synthesise the evidence for each outcome, if possible. The heterogeneity will be statistically assessed using a χ ETHICS AND DISSEMINATION: Ethics approval is not required for this review. Our findings will be published in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42024601226.

Indexed as

Acupuncture TherapyInfertility, FemalePolycystic Ovary SyndromePregnancy OutcomeFemaleHumansMeta-Analysis as TopicPregnancyPregnancy RateRandomized Controlled Trials as TopicResearch DesignSystematic Reviews as TopicAcupunctureMeta-AnalysisPregnancySubfertilitySystematic Review

Identifiers

PMID40645631
PMCPMC12248215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.