Evidence map›Paper›PMID 40644125›Full record

ArticleIEEE ... International Conference on Rehabilitation Robotics : [proceedings]2025

Evaluating the Relationship Between Motor and Cognitive Impairment and Lesion Size and Location Post-Stroke Using CT Scans.

Reem M Azar, Natalia Stroutinsky Sobotka, Pamela Cacchione, Rochelle J Mendonca, Michelle J Johnson

Abstract read
In one paragraph

Article in IEEE ... International Conference on Rehabilitation Robotics : [proceedings], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Modeling Post-Stroke Motor Behavior from Structural Lesion Networks: A Preliminary Study with Robot-Based Assessments.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reem M Azar
Natalia Stroutinsky Sobotka
Pamela Cacchione
Rochelle J Mendonca
Michelle J Johnson

Funding

Training Program in Musculoskeletal ResearchT32AR007132 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Robert L Mauck, LOUIS J SOSLOWSKY · 1986 to 2026
$4.9M
Rehabilitation Using Community-Based Affordable Robotic Exercise Systems (Rehab CARES)R42HD104325 · NICHD · RECUPERO ROBOTICS LLC · PI JOHNSON, ALWYN P., JOHNSON, MICHELLE J. · 2021 to 2023
$1.8M
NIAMS NIH HHS T32 AR007132NICHD NIH HHS R42 HD104325
6 · The paper itself

Abstract

With stroke being the leading cause of disability worldwide, there is a need to improve current rehabilitative care. Stroke causes brain damage in the form of a lesion, resulting in both cognitive and motor deficits. Clinicians often rely on functional behavior to determine treatment directions; however, behavioral deficit may not represent the neural damage. Understanding how the neural damage influences the behavioral impairments with stroke subjects could allow clinicians to provide a more personalized therapeutic plan. Focusing on global accessibility, CT-scans were used to image the lesion given that it is an affordable imaging modality that is used world-wide. Eleven chronic stroke patients were mapped into functional groups by their motor and cognitive behavior and their CT-scans was used to quantify lesion volume and define how the volume location mapped unto the whole brain areas at different granular levels. Our main findings were that lesion size may not be a good indicator of behavioral deficit. These results suggest that assessing brain areas more granularly may show larger differences in behavior.

Indexed as

Cognition DisordersStrokeTomography, X-Ray ComputedAdultAgedBrainFemaleHumansMaleMiddle AgedStroke Rehabilitation

Identifiers

PMID40644125
PMCPMC12861172

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.