Evidence map›Paper›PMID 40643842›Full record

ArticleAdvances in therapy2025

Broad Impact of Bowel Urgency in Ulcerative Colitis and Crohn's Disease: US, European, and Japanese Patient and Healthcare Professional Perspectives from the Communicating Needs and Features of IBD Experiences (CONFIDE) Survey.

David T Rubin, Alison Potts Bleakman, Simon Travis, Marla Dubinsky, Stefan Schreiber, Remo Panaccione, Theresa Hunter Gibble, Cem Kayhan, Tommaso Panni, Eoin Flynn and 4 more

Abstract read
In one paragraph

Article in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David T RubinUniversity of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, USA. drubin@bsd.uchicago.edu.ORCID http://orcid.org/0000-0001-5647-1723
Alison Potts BleakmanEli Lilly and Company, Indianapolis, USA.
Simon TravisUniversity of Oxford, Oxford, UK.
Marla DubinskyIcahn School of Medicine at Mount Sinai, New York, USA.
Stefan SchreiberUniversity Hospital Schleswig-Holstein, Kiel, Germany.
Remo PanaccioneUniversity of Calgary, Calgary, Canada.
Theresa Hunter GibbleEli Lilly and Company, Indianapolis, USA.
Cem KayhanEli Lilly and Company, Indianapolis, USA.
Tommaso PanniEli Lilly and Company, Indianapolis, USA.
Eoin FlynnEli Lilly and Company, Indianapolis, USA.
Angelo D FaviaEli Lilly and Company, Indianapolis, USA.
Christian AtkinsonAdelphi Real World, Bollington, UK.
Sonal SaxenaEli Lilly and Company, Indianapolis, USA.
Toshifumi HibiKitasato University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBowel urgency affects the quality of life of patients with Crohn's disease (CD) and ulcerative colitis (UC). This study used data from the Communicating Needs and Features of IBD Experiences (CONFIDE) survey to explore patient and healthcare professional (HCP) perceptions on the broad impacts of bowel urgency on patients' emotions and daily lives.

methodsOnline, quantitative, cross-sectional surveys were conducted among patients with moderate-to-severe UC or CD (defined based on previous treatment, steroid use, and/or hospitalization) and HCPs specialized in gastroenterology in Europe (France, Germany, Italy, Spain, UK), United States (US), and Japan. Data were summarized using descriptive statistics.

resultsThe analysis included 200 US, 556 European, and 124 Japanese patients with UC and 215 US, 547 European, and 99 Japanese patients with CD; and 200 US, 503 European, and 100 Japanese HCPs. Patients experiencing bowel urgency in the past month and HCPs reported high emotional (up to: 97% patients, 97% HCPs) and daily life (up to: 85% patients, 97% HCPs) impacts due to bowel urgency in the US, Europe, and Japan. In all geographies, these impacts were similar among patients with UC and CD. Although patients and HCPs reported a broad impact of bowel urgency, HCPs perceived a higher impact than patients, but it was not among the top three most impactful symptoms on HCPs' treatment decisions.

conclusionsBowel urgency affects the emotions and daily life of patients with UC or CD in the US, Europe, and Japan. A multidisciplinary approach is required to enhance care and develop suitable treatment strategies.

Indexed as

Colitis, UlcerativeCrohn DiseaseQuality of LifeAdultAttitude of Health PersonnelCross-Sectional StudiesEast Asian PeopleEuropeFemaleHumansJapanMaleMiddle AgedSurveys and QuestionnairesUnited StatesBowel urgencyCrohn’s diseaseUlcerative colitis

Identifiers

PMID40643842
PMCPMC12394242

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.