Evidence map›Paper›PMID 40643708›Full record

ArticleLangenbeck's archives of surgery2025

Comparative outcomes of intracorporeal and extracorporeal anastomosis following laparoscopic colectomy in patients with obesity with Colon cancer.

Feng-Ching Tsai, Yih Jong Chern, Yu-Jen Hsu, Chun-Kai Liao, Ching-Chung Cheng, Wen-Sy Tsai, Pao-Shiu Hsieh, Jeng-Fu You

Abstract readComparative Study
In one paragraph

Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Feng-Ching TsaiDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Yih Jong ChernDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Yu-Jen HsuDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Chun-Kai LiaoDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Ching-Chung ChengDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Wen-Sy TsaiDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Pao-Shiu HsiehDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan.
Jeng-Fu YouDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan, Taiwan. jenodyssey@gmail.com.

Funding

Chang Gung Medical Research Fund CMRPG3J1531
6 · The paper itself

Abstract

purposeLaparoscopic surgery with intracorporeal anastomosis (IA) is a well-established procedure in colorectal cancer surgery. Nonetheless, its feasibility in patients with obesity remains unclear. This study aimed to evaluate the short-term and medium-term outcomes of IA to extracorporeal anastomosis (EA) among a cohort of patients with general obesity treated at a single teaching hospital.

methodsThe study included patients with obesity who underwent laparoscopic radical colectomy with primary bowel anastomosis for colon cancer between September 2007 and December 2021. Patients were split into two groups according to the method of anastomosis used: EA or IA. We evaluated various surgical outcomes, namely postoperative complications, recovery metrics, pain intensity, and 3-year survival rates.

resultsA total of 355 patients with obesity with colorectal cancer were enrolled in the study. 150 and 205 patients were in the IA and EA groups, respectively. The IA group demonstrated faster bowel recovery, faster resumption of diet, and shorter hospital stays compared with the EA group. Additionally, IA yielded specimens with longer lengths and larger safety margins relative to the tumor. The EA group exhibited a significantly higher overall rate of postoperative complications, most notably postoperative ileus. However, the 3-year oncological outcomes were similar between the IA and EA groups.

conclusionThe study revealed that in patients with obesity, IA resulted in faster bowel function recovery, shorter hospital stays, and fewer complications. Furthermore, IA produced better pathological outcomes, characterized by longer specimen lengths and wider safety margins, without compromising 3-year overall and disease-free survival rates. Thus, IA is a safe and feasible anastomosis technique for patients with obesity undergoing laparoscopic colectomy for colorectal cancer.

Indexed as

Anastomosis, SurgicalColectomyColonic NeoplasmsLaparoscopyObesityAgedFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeColectomyIntracorporeal anastomosisLaparoscopic surgeryObesity

Identifiers

PMID40643708
PMCPMC12254073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.