Evidence map›Paper›PMID 40643654›Full record

ReviewAbdominal radiology (New York)2026

Diffusion-weighted imaging in rectal cancer MRI from theory to practice.

Debora Mayumi Takamune, João Miranda, Miriana Mariussi, Thais Reif de Paula, Yousef Mazaheri, Eyesha Younus, Krishan R Jethwa, Cody C Knudsen, Valesca Bizinoto, Daniel Cardoso and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Diffusion MRI of the Body: Beyond PGSE-EPI.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Debora Mayumi TakamuneHospital Sírio-Libanês, São Paulo, Brazil.
João MirandaMayo Clinic, Rochester, USA.
Miriana MariussiHospital Israelita Albert Einstein, São Paulo, Brazil.
Thais Reif de PaulaLankenau Medical Center, Philadelphia, USA.
Yousef MazaheriMemorial Sloan Kettering Cancer Center, New York, USA.
Eyesha YounusMayo Clinic, Rochester, USA.
Krishan R JethwaMayo Clinic, Rochester, USA.
Cody C KnudsenMayo Clinic, Rochester, USA.
Valesca BizinotoUniversidade de São Paulo, São Paulo, Brazil.
Daniel CardosoHospital Sírio-Libanês, São Paulo, Brazil.
José de Arimateia Batista Araujo-FilhoHospital Sírio-Libanês, São Paulo, Brazil.
Carlos Frederico Sparapan MarquesUniversidade de São Paulo, São Paulo, Brazil.
Cesar Higa NomuraUniversidade de São Paulo, São Paulo, Brazil.
Natally HorvatMayo Clinic, Rochester, USA. horvat.natally@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffusion-weighted imaging (DWI) has become a cornerstone of high-resolution rectal MRI, providing critical functional information that complements T2-weighted imaging (T2WI) throughout the management of rectal cancer. From baseline staging to restaging after neoadjuvant therapy and longitudinal surveillance during nonoperative management or post-surgical follow-up, DWI improves tumor detection, characterizes treatment response, and facilitates early identification of tumor regrowth or recurrence. This review offers a comprehensive overview of DWI in rectal cancer, emphasizing its technical characteristics, optimal acquisition strategies, and integration with qualitative and quantitative interpretive frameworks. The manuscript also addresses interpretive pitfalls, highlights emerging techniques such as intravoxel incoherent motion (IVIM), diffusion kurtosis imaging (DKI), and small field-of-view DWI, and explores the growing role of radiomics and artificial intelligence in advancing precision imaging. DWI, when rigorously implemented and interpreted, enhances the accuracy, reproducibility, and clinical utility of rectal MRI.

Indexed as

Diffusion Magnetic Resonance ImagingRectal NeoplasmsHumansNeoplasm StagingReproducibility of ResultsDiffusion magnetic resonance imagingMagnetic resonance imagingNeoadjuvant therapyRectal neoplasm

Identifiers

PMID40643654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.