Evidence map›Paper›PMID 40643649›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Effect of hydrogen-enriched water on healing of excisional full-layer skin wounds in diabetic and non-diabetic rats.

Muhammed Deniz, Yeliz Akkuş, Gülden Yıldız, Hatice Beşeren Havadar, Mustafa Makav

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Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammed DenizDepartment of Surgical Nursing, Faculty of Health Sciences, Kafkas University, Kars, Turkey. m.deniz476474@gmail.com.ORCID 0000-0001-6129-9526
Yeliz AkkuşDepartment of Internal Medicine Nursing, Faculty of Health Sciences, Kafkas University, Kars, Turkey.ORCID 0000-0002-9321-2357
Gülden YıldızDepartment of Medical Pathology, Medical Faculty Hospital, Kafkas University, Kars, Turkey.ORCID 0000-0003-1530-8529
Hatice Beşeren HavadarMedical Pathology Laboratory, Faculty of Medicine Hospital, Kafkas University, Kars, Turkey.ORCID 0000-0002-4780-540X
Mustafa MakavDepartment of Veterinary Physiology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID 0000-0003-1879-8180

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was carried out in an experimental study design with experimental and control groups to investigate the effect of hydrogen-enriched water (HRW) on healing in excisional full-layer skin wounds. The rats were divided into diabetic group (n = 20) and non-diabetic group (n = 18) (n = 38). Diabetic group was divided into three groups as diabetic wound (DC), diabetic wound saline (DS), and diabetic wound hydrogen-enriched water (DH2); and control group was divided into three groups as non-diabetic wound (non-DC), non-diabetic wound saline (non-DS), and non-diabetic wound hydrogen-enriched water (non-DH2). Streptozotocin (STZ) was given to induce diabetes in rats in the diabetic group. An average of 1.9 cm

Indexed as

Diabetes Mellitus, ExperimentalHydrogenSkinWaterWound HealingAnimalsInterleukin-6MaleRatsRats, WistarTumor Necrosis Factor-alphaHydrogenInterleukin-6Tumor Necrosis Factor-alphaWaterDiabetesHydrogen-enriched waterRatWound care in nursingWound healing

Identifiers

PMID40643649

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.