Evidence map›Paper›PMID 40643456›Full record

ArticleMagyar onkologia2025

[The effect of PSMA PET/CT performed in primary staging on the clinical decision].

Zsófia Küronya, Péter Ágoston, Kliton Jorgo, László Gesztesi, Bence Kapuvári, Péter Dombovári, Stelios Mavrogenis, Lajos Géczi, Enikő Lénárt, Tamás Dienes and 4 more

Abstract readEnglish Abstract
In one paragraph

Article in Magyar onkologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zsófia KüronyaUrogenitális Tumorok és Klinikai Farmakológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuronya.zsofia@oncol.hu.
Péter ÁgostonSugárterápiás Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Kliton JorgoSugárterápiás Központ, Országos Onkológiai Intézet, Budapest, Hungary.
László GesztesiSugárterápiás Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Bence KapuváriMolekuláris Immunológia és Toxikológia Osztály, Országos Onkológiai Intézet, Biokémiai Részleg és Nemzeti Tumorbiológiai Laboratórium, Budapest, Hungary.
Péter DombováriUrológiai Daganatsebészeti Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Stelios MavrogenisUrológiai Daganatsebészeti Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Lajos GécziUrogenitális Tumorok és Klinikai Farmakológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuronya.zsofia@oncol.hu.
Enikő LénártUrogenitális Tumorok és Klinikai Farmakológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuronya.zsofia@oncol.hu.
Tamás DienesUrogenitális Tumorok és Klinikai Farmakológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuronya.zsofia@oncol.hu.
Sándor ManningerOnkológiai Képalkotó és Invazív Diagnosztikai Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Szabolcs SzakállPozitron-Diagnosztika Központ, Budapest, Hungary.
Tamás MartinThe Royal Marsden NHS Foundation Trust, London, UK.
Krisztina BiróUrogenitális Tumorok és Klinikai Farmakológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuronya.zsofia@oncol.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOur study aimed to conduct a retrospective statistical analysis of 18F-JK-PSMA-7 PET/CT results in high-risk prostate cancer patients as part of primary staging, to assess how these results influenced the original treatment plan.

methodsThe study included high-risk prostate adenocarcinoma patients, localized by conventional imaging, who underwent PSMA PET/CT as part of primary staging between 03/01/2020 and 03/01/2022.

resultsPSMA PET/CT confirmed distant metastasis in 20 out of 74 patients. Among them, 7 received local treatment due to oligometastatic disease. The remaining 13 patients had distant lymph node metastasis (1 patient), bone metastasis only (2 patients), or both (10 patients). Based on PSMA PET/CT results, these 13 patients received systemic treatment instead of local therapy. No significant statistical correlation was found between PSA levels, ISUP score, and distant metastasis verification.

conclusionBroader use of PSMA PET/CT in primary staging of high-risk prostate cancer patients could allow for more precise, personalized therapy in the future.

Indexed as

AdenocarcinomaPositron Emission Tomography Computed TomographyProstatic NeoplasmsAgedAged, 80 and overAntigens, SurfaceBone NeoplasmsClinical Decision-MakingGlutamate Carboxypeptidase IIHumansLymphatic MetastasisMaleMiddle AgedNeoplasm StagingProstate-Specific AntigenRadiopharmaceuticalsAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIProstate-Specific AntigenRadiopharmaceuticals

Identifiers

PMID40643456
PMCPMC12255501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.