Evidence map›Paper›PMID 40643449›Full record

ReviewMagyar onkologia2025

[Overall survival, organ preservation, function preservation: the role of surgery in the treatment of laryngeal cancer].

Kornél Dános, László Tamás

Abstract readReviewEnglish Abstract
In one paragraph

Review in Magyar onkologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kornél DánosFül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem, Budapest, Hungary. danos.kornel@semmelweis.hu.
László TamásFül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem, Budapest, Hungary. danos.kornel@semmelweis.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of early stage laryngeal carcinoma treated with radiation therapy or surgery (preferably transoral resection) is favorable. In these cases, the choice of the therapy is mainly driven by functional outcomes (speech, swallowing and respiratory function). However, there has not been any substantial improvement in the treatment of locoregionally advanced larynx cancer. The selection of the most ideal therapy is difficult, as upfront total laryngectomy is rather radical, and has a dramatic effect on quality of life, whereas reliable predictors of radiosensitivity are lacking. Moreover, current data undermines the oncologic effectiveness of salvage laryngectomy. In this review, we summarize the current anatomical and functional facts and concepts with respect to the previous clinical trials and studies that might influence the decision making during the treatment of a laryngeal cancer patient in 2025.

Indexed as

Laryngeal NeoplasmsLaryngectomyOrgan Sparing TreatmentsHumansNeoplasm StagingPrognosisQuality of LifeSalvage TherapyTreatment Outcome

Identifiers

PMID40643449
PMCPMC12255503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.