Evidence map›Paper›PMID 40643376›Full record

SynthesisAmerican journal of epidemiology2025

Emotional and instrumental social support and older adults' depressive symptoms: collaborative individual participant data meta-analysis of 11 population-based studies of aging.

Suraj Samtani, Gowsaly Mahalingam, Ben C P Lam, Darren M Lipnicki, Katya Numbers, Maria Fernanda Lima-Costa, Sergio Luis Blay, Erico Castro Costa, Shifu Xiao, Steffi Reidel-Heller and 20 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Suraj SamtaniCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0002-9957-1916
Gowsaly MahalingamCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.
Ben C P LamCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.
Darren M LipnickiCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0002-1684-3577
Katya NumbersCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0002-7009-2401
Maria Fernanda Lima-CostaRené Rachou Research Center, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.ORCID 0000-0003-4309-4548
Sergio Luis BlayDepartment of Psychiatry, Federal University of Sao Paulo-UNIFESP, Sao Paulo, Brazil.ORCID 0000-0002-0568-9375
Erico Castro CostaCenter for Studies in Public Health and Aging, René Rachou Research Center, Belo Horizonte, Brazil.ORCID 0000-0003-0792-5439
Shifu XiaoDepartment of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, 600 South Wan Ping Road, Shanghai 200030, China.ORCID 0000-0002-4721-9646
Steffi Reidel-HellerFaculty of Medicine, Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.ORCID 0000-0003-4321-6090
Susanne RöhrCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0001-9385-0669
Alexander PabstFaculty of Medicine, Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.ORCID 0000-0003-0432-5681
Nikolaos Scarmeas1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, 72 Vasilisis Sofias Avenue, Athens 11528, Greece.ORCID 0000-0001-6453-8908
Mary YannakouliaDepartment of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, Athens, Greece.ORCID 0000-0003-2171-7337
Mary KosmidisLaboratory of Neuropsychology & Behavioral Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.ORCID 0000-0001-8790-1220
Murali KrishnaInstitute of Public Health, Bangalore 560070, India.
Kalyanaraman KumaranThe Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.ORCID 0000-0002-6107-8608
Suzana ShaharFaculty of Health Sciences, Community Rehabilitation and Aging Research Centre, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 43000 Kuala Lumpur, Malaysia.ORCID 0000-0002-7191-9212
Tze Pin NgDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Level 9, NUHS Tower Block, 1E Kent Ridge Road, 119228, Singapore.ORCID 0000-0001-9585-855X
Roger HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Level 9, NUHS Tower Block, 1E Kent Ridge Road, 119228, Singapore.ORCID 0000-0001-9629-4493
Ki-Woong KimDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, 300 Gumiro, Bundanggu, Seongnamsi, Gyeonggido 463-707, Seoul, South Korea.ORCID 0000-0002-1103-3858
Ingmar SkoogDepartment of Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, Centre for Ageing and Health (AGECAP), University of Gothenburg, Mölndal, Sweden.ORCID 0000-0002-9803-3438
Jenna NajarDepartment of Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, Centre for Ageing and Health (AGECAP), University of Gothenburg, Mölndal, Sweden.ORCID 0000-0002-1762-4413
Therese Rydberg SternerDepartment of Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, Centre for Ageing and Health (AGECAP), University of Gothenburg, Mölndal, Sweden.ORCID 0000-0001-8202-8522
Mary GanguliDepartment of Psychiatry, Epidemiology and Neurology, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-2762-7105
Chung-Chou Ho ChangDepartment of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-3665-6928
Tiffany F HughesYoungstown State University, Youngstown, OH, United States.
Perminder S SachdevCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0002-9595-3220
Henry BrodatyCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW  Sydney, NSW 2052, Australia.ORCID 0000-0001-9487-6617
Cohort Studies of Memory in an International Consortium (COSMIC)

Funding

Mild Cognitive Impairment: A Prospective Community StudyR37AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carmen Andreescu, MARY GANGULI · 2021 to 2026
$18.2M
A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC CollaborationR01AG057531 · NIA · UNIVERSITY OF NEW SOUTH WALES · PI Perminder S SACHDEV · 2023 to 2026
$5.9M
COSMIC: An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethno-racial groups and geographical settingsRF1AG057531 · NIA · UNIVERSITY OF NEW SOUTH WALES · PI SACHDEV, PERMINDER S · 2017 to 2020
$2.9M
AgeCap-Center for Aging and Health, Riksbankens Jubileumsfond, FORTE, and the Swedish Brain PowerALF-agreement 7,2660Alzheimer's Association, European Social Fund, and Greek Ministry of HealthAlzheimersfonden AF-967865Biomedical Research Council, Agency for Science, Technology and Research, Singapore 03/1/21/17/214Financiadora de Estudos e Projetos (FINEP), Conselho Nacional de Desenvolvimento Científico e Tecnológicos (CNPq), and Fundação de Amparo Pesquisa do Estado de Minas Gerais (FAPEMIG)Interdisciplinary Centre for Clinical Research at the University of Leipzig 01KS9504Korean Health Technology R&D Project, Ministry of Health and Welfare, South Korea HI09C1379 [A092077]Ministry of Higher Education of Malaysia LRGS/BU/2012/UKM-UKM/K/01Ministry of Science and Technology, National Pillar Program 2009BAI77B03National Health and Medical Research Council APP350833, APP568969, and APP1093083National Institute on Aging of the National Institutes of Health RF1AG057531 and 2R01AG057531-02A1National Key Clinical Disciplines at Shanghai Mental Health Center 2011-873NIA NIH HHS R01 AG057531NIA NIH HHS R37 AG023651NIA NIH HHS RF1 AG057531NIA to the University of Pittsburgh R37AG023651Stiftelsens Hjalmar Svenssons forskningsfond HJSV2022059, HJSV2023023The Swedish Research Council, Swedish Research Council for Health, Working Life and Welfare, Epilife, Swedish Brain Power, The Alzheimer's Association Zenith Award, The Alzheimer's Association Stephanie B Overstreet Scholars, The Bank of Sweden Tercentenary Foundation, Stiftelsen Söderström-Königska Sjukhemmet, Stiftelsen för Gamla Tjänarinnor, Handlanden Hjalmar Svenssons Forskningsfond, and Stiftelsen Professor Bror Gadelius' Minnesfond
6 · The paper itself

Abstract

Social support is considered a protective factor against depression, but there are inconsistent findings regarding social support and depression in older adults. We aimed to clarify the association between emotional and instrumental social support and depressive symptoms in older adults cross-sectionally and longitudinally (mean follow-up = 1.96 years). We meta-analyzed raw individual participant level data from adults in mid- and late life (N = 23 973) who completed questionnaires about physical health, mental health, and social support and completed neuropsychological assessments. These were COSMIC (Cohort Studies of Memory in an International Consortium) cohort studies carried out in Australia, Brazil, China, Germany, Greece, India, Indonesia, Singapore, South Korea, Sweden, and the United States in mostly urban settings. After controlling for depression risk factors, emotional support (B = -0.40 [95% CI, -0.60 to -0.21]), but not instrumental support (B = 0.17 [95% CI, -0.26 to 0.59]), was associated with lower depressive symptoms cross-sectionally and at follow-up [emotional support (B = -0.37 [95% CI, -0.54 to -0.20]); instrumental support (B = 0.09 [95% CI, -0.30 to 0.49])]. Emotional support was associated with lower depressive scores cross-sectionally and longitudinally, while instrumental support was not associated with depressive symptoms. Our findings can help inform the nature of interventions to prevent and reduce risk of depression among older adults. This article is part of a Special Collection on Cross-National Gerontology.

Indexed as

AgingDepressionEmotionsSocial SupportAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk Factorsdepressionlate lifeolder adultsprotectivesocial support

Identifiers

PMID40643376
PMCPMC12527255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.