ArticleInvestigative ophthalmology & visual science2025
Interocular Differences in Retinal Curvature in Anisometropic Patients and Their Association With Myopic Degree Differences.
Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Understanding the link between ocular shape and myopia: a systematic review.BMJ open ophthalmology · 2026Pooled it
- Motion-corrected Gaussian, mean, and parametric curvature mapping of the posterior eye with pupil-tracked whole-eye OCT.Biomedical optics express · 2026Article
- The Changing Natural History of Anisometropia: A Scoping Review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate regional differences in Gaussian retinal curvature (RC) between fellow eyes of anisometropic patients and their associations with interocular disparities in myopic parameters. Methods: In this cross-sectional study, ultra-widefield swept-source optical coherence tomography (24 mm × 20 mm field) was performed in 121 anisometropic patients. Three-dimensional retinal morphology reconstruction based on Bruch's membrane was used to derive Gaussian RC. The retina was segmented into macular, peripheral, and six concentric annular regions (I-VI). Paired t-tests or Wilcoxon signed-rank tests were applied to evaluate interocular RC differences, with Spearman correlation analysis examining associations between RC variations and myopic parameter disparities. Results: Mean interocular differences were 1.95 ± 0.95 D for spherical equivalent (SE) and 0.79 ± 0.46 mm for axial length (AL). The more myopic eye exhibited significantly steeper macular RC (P < 0.001) and flatter peripheral RC (P < 0.001) compared to the fellow eye. Macular/peripheral RC disparities demonstrated significant correlations with SE/AL differences (both P < 0.05). Region-specific analysis revealed positive correlations between AL and RC I-III differentials, whereas inverse correlations were observed for RC V-VI (all P < 0.01). Conclusions: Anisometropic patients demonstrate biomechanical divergence characterized by macular steepening and peripheral flattening in the more myopic eye during axial elongation, suggesting region-dependent retinal adaptation mechanisms.
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