Evidence map›Paper›PMID 40643157›Full record

ArticleActa obstetricia et gynecologica Scandinavica2025

Preterm birth in Latvia: Two-decade national trends, structure, and risk factors.

Diana Andzane, Ludmila Volozonoka, Maksims Zolovs, Anna Kornete, Dace Rezeberga, Anna Miskova

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diana AndzaneRiga Maternity Hospital, Riga, Latvia.ORCID 0000-0001-7924-8532
Ludmila VolozonokaInstitute of Oncology and Molecular Genetics, Rīga Stradiņš University, Riga, Latvia.ORCID 0000-0003-0413-1481
Maksims ZolovsStatistics Unit, Rīga Stradiņš University, Riga, Latvia.ORCID 0000-0001-9120-5869
Anna KorneteRiga Maternity Hospital, Riga, Latvia.ORCID 0000-0002-5363-8134
Dace RezebergaRiga Maternity Hospital, Riga, Latvia.ORCID 0000-0001-6287-7017
Anna MiskovaRiga Maternity Hospital, Riga, Latvia.ORCID 0000-0002-1592-1852

Funding

Fundamental and Applied Research Projects grant of The Latvian Council of Science. Project 'Elucidating comprehensive etiology of cervical insufficiency to foster timely diagnosis of preterm delivery and prevent adverse outcomes in obstetrics' 2020/1-0042
6 · The paper itself

Abstract

introductionLatvia, alongside other Baltic and Nordic countries, exhibits some of the world's lowest preterm birth (PTB) rates. We sought to identify the factors sustaining this stability and to examine how PTB structure, trends, and risk factors have evolved in Latvia over time, amid the nation's significant socioeconomic transformation in recent decades. MATERIAL AND

methodsThis retrospective study analyzed all term and PTBs in Latvia from 2000 to 2023, using data from the Disease Prevention and Control Centre's Health Statistics database. We evaluated records at 5-year intervals, assessing temporal trends in PTB and term birth outcomes, including neonatal and perinatal mortality, labor onset (spontaneous or indicated), and prematurity subgroups, alongside known PTB risk factors (n = 16). Joinpoint regression identified significant trend shifts, with statistical significance set at p < 0.05.

resultsLatvia's overall PTB rate remained stable at 5.5% from 2000 to 2023, with no significant trend, while the proportion of spontaneous versus indicated PTB changed over time. Spontaneous extremely PTB decreased by 0.7% every 5 years, from 8.5% in 2000 to 5.2% in 2023 (p = 0.005), and very to moderate PTB declined by 1.3% every 5 years, from 26.2% to 19.5% over the same period (p = 0.011). A significant upward trend was identified in the total indicated PTB rate, with an increase of 3.3% every 5 years, rising from 12.5% in 2000 to 29.2% in 2023 (p = 0.036), driven by the increase in late indicated PTBs. Perinatal mortality for PTB in Latvia declined significantly by 1.21% every 5 years, from 13.15% in 2000 to 7.09% in 2023 (p = 0.005). Primiparity, smoking, urinary tract infections, and lower education levels among PTB mothers decreased significantly, while maternal age, previous cesarean sections, and intrauterine growth restriction as PTB risk factors increased.

conclusionsDespite PTB structure and risk factor shifts, Latvia's 5.5% PTB rate remained stable over two decades, with indicated PTB rising due to expanded late preterm indications. Improved neonatal and perinatal mortality reflect effective guidelines, socioeconomic growth, and care investments, countering adverse trends.

Indexed as

Premature BirthAdultFemaleHumansInfant, NewbornLatviaPerinatal MortalityPregnancyRetrospective StudiesRisk FactorsLatviamaternal ageperinatal mortalitypregnancy outcomepreterm birthpublic healthrisk factorsstatistics

Identifiers

PMID40643157
PMCPMC12451207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.