Evidence map›Paper›PMID 40643135›Full record

Observational studyJournal of global health2025

Prevalence and factors with potentially inappropriate prescribing among older outpatients with depression: a multicentre study across China.

Fangyuan Tian, Zhaoyan Chen, Ying Zhang

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fangyuan TianDepartment of Pharmacy, National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Zhaoyan ChenDepartment of Pharmacy, National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Ying ZhangDepartment of Pharmacy, National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Older outpatients with depression are at high risk for potentially inappropriate prescription (PIP). This investigation sought to determine the frequency and associated factors of PIP within Chinese older adults. Methods: This cross-sectional study used prescription data from older outpatients with depression from 90 hospitals in seven cities in China from January-December 2021. Risk factor identification for PIP employed multivariate logistic regression analysis. Trend assessment was performed through joinpoint regression to calculate the average annual percent change. Results: The prevalence of PIP reached 50.42%. The top five PIM were alprazolam, clonazepam, olanzapine, lorazepam, estazolam. The prevalence of PIP decreased from 51.56 to 50.99% (average annual percent change = -0.335%). Logistic regression demonstrated that tertiary-level hospital (odds ratio (OR) = 1.215; 95% confidence interval (CI) = 1.100, 1.342, P < 0.001), department of psychiatry (OR = 1.958; 95% CI = 1.855, 2.067, P < 0.001), age ≥80 (OR = 1.069; 95% CI = 1.016, 1.124, P = 0.01), more diseases (OR = 1.209; 95% CI = 1.092, 1.339, P < 0.001), polypharmacy (OR = 1.672; 95% CI = 1.541, 1.814, P < 0.001) exhibited positive links to PIP among older outpatients suffering from depression. Conclusions: This investigation revealed that the occurrence of PIP in older outpatients with depression is high in China.

Indexed as

Antidepressive AgentsDepressionInappropriate PrescribingOutpatientsAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsAntidepressive Agents

Identifiers

PMID40643135
PMCPMC12256811

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