Trial reportSexually transmitted diseases2025
Participants and Recipients in Social Network Distribution of HIV Self-Testing Kits Among Men Who Have Sex With Men in China.
Trial report in Sexually transmitted diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
10 authors.
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Abstract
backgroundSecondary distribution of human immunodeficiency virus (HIV) self-testing (HIVST) kits offers a promising strategy to expand testing among marginalized men who have sex with men (MSM). We compared characteristics of kit distributors (index participants) and recipients, and identified predictors of HIV testing and kit distribution.
methodsWe analyzed data from a randomized controlled trial among MSM in Zhuhai, China (2019-2020). Regression models identified predictors of HIV testing and kit distribution.
resultsA total of 303 index participants and 264 recipients were included. Index participants were more likely than recipients to have previously tested for HIV (84.5% vs 62.5%), report recent (past 3 months) male-male anal intercourse (83.2% vs 60.6%), and have multiple male partners (52.8% vs 40.6%). Among index participants, HIV testing was associated with older age (per year increase: adjusted odds ratio [aOR], 1.14; 95% confidence interval [CI], 1.05-1.24), higher education (college vs high school or below: aOR, 4.71; 95% CI, 1.94-11.6), and condomless sex (aOR, 3.90; 95% CI, 1.37-12.9). Among recipients, higher income ($451-750: aOR, 2.58; 95% CI, 1.11-6.00; $751-1200; aOR, 2.35; 95% CI, 1.04-5.36, vs <$450) was linked to prior testing. Approximately 45% of index participants distributed HIVST kits to recipients. Distribution was positively associated with older age (incidence rate ratio [IRR], 1.03; 95% CI, 1.00-1.07), graduate education (vs high school or below: IRR, 2.18; 95% CI, 1.05-4.54), and number of sexual partners (IRR, 1.09; 95% CI, 1.02-1.17).
conclusionsTailored HIVST interventions using social network-based distribution can enhance HIV testing coverage among MSM. This strategy may improve testing uptake in low- and middle-income countries but requires further investigation.
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