Risk of anaphylaxis on commercial flights.

purpose of reviewAir travel has now returned to prepandemic levels, with over 10.5 billion passengers in 2024. Many of these passengers have food allergies, and there is a perception that allergic reactions are common during commercial flights. RECENT

findingsA recent systematic review and meta-analysis reported an incidence of in-flight medical events due to allergic reactions of 0.7 (95% CI 0.4-1.1) events per million passengers. For those with food allergies, the incidence of allergic reactions is around 10-100 times lower than that reported for reactions 'on the ground' - equivalent to one reaction per 3600 food-allergic passengers in any 1-year period. Reassuringly, there is no evidence that this rate had increased over the past 30 years, despite significant increases in both the prevalence of food allergy and passenger numbers. SUMMARY: Allergic reactions during commercial flights are uncommon; however, this is very likely to be confounded by the many precautions food-allergic passengers and their families take when flying. Nonetheless, the data confirm that flying can be safe for those with food allergies. While air travel continues to present numerous challenges to those with food allergy, this can be mitigated by consistent and helpful airline policies, which address the concerns of food-allergic individuals.