Evidence map›Paper›PMID 40643040›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2025

Designing the Next Generation of Biomaterials through Nanoengineering.

Ryan Davis, Ishaan Duggal, Nicholas A Peppas, Akhilesh K Gaharwar

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
  3. Review
  4. Tissue-specific gene delivery approaches.Bioengineering & translational medicine · 2026
    Review
  5. Article
  6. Article
  7. Materiobiology in the omics era.Materials today. Bio · 2025
    Review
  8. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan DavisDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, 77843, USA.
Ishaan DuggalInstitute for Biomaterials, Drug Delivery, and Regenerative Medicine, The University of Texas at Austin, Austin, TX, 78712, USA.
Nicholas A PeppasInstitute for Biomaterials, Drug Delivery, and Regenerative Medicine, The University of Texas at Austin, Austin, TX, 78712, USA.
Akhilesh K GaharwarDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, 77843, USA.ORCID https://orcid.org/0000-0002-0284-0201

Funding

Osteoinductive Nanosilicate-Based Biomaterials for In Situ Craniomaxillofacial Bone RegenerationR01DE032031 · NIDCR · TEXAS ENGINEERING EXPERIMENT STATION · PI CARL A. GREGORY, Akhilesh K. Gaharwar · 2024 to 2026
$1.7M
Sensor arrays based on molecularly imprinted polymers for diagnosis of Sjogren's syndromeR01EB022025 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI ANSLYN, ERIC V., PEPPAS, NICHOLAS A · 2016 to 2019
$1.5M
IMSD at Texas A&M University: Initiative for Maximizing Student Diversity in Biomedical SciencesT32GM135748 · NIGMS · TEXAS A&M UNIVERSITY · PI BRINKMEYER-LANGFORD, CANDICE L., CHIU, WEIHSUEH A · 2020 to 2024
$1.2M
Congressionally Directed Medical Research Programs W81XWH2210932NIBIB NIH HHS EB022025NIBIB NIH HHS R01 EB022025NIDCR NIH HHS R01 DE032031NIGMS NIH HHS T32 GM135748
6 · The paper itself

Abstract

Recent advances in biomaterials science have applied nanoengineering to develop biomaterials with superior properties and tailored functionalities. These unique attributes are achieved due to the ability of nanoengineering to provide precise control over material interactions with living systems at the molecular scale. Here, key nanotechnologies employed to develop the next generation of biomaterials are critically evaluated. A diverse range of nanomaterials, differing in base materials, shapes, sizes, or surface properties can be integrated into various fabrication processes to develop these advanced biomaterials. Further investigation is required into properties such as surface energy, defects, porosity, and crystallinity, as these critically influence the physical, chemical, and biological characteristics of nanoengineered materials. Consequently, we explore diverse biomedical applications of nanoengineered biomaterials, including regenerative medicine, biomolecular delivery, additive manufacturing, immune engineering, cancer therapeutics, bioimaging, biosensing, antimicrobial devices, and tissue adhesives. Additionally, their current limitations are analyzed and emerging strategies for designing the next generation of nanoengineered biomaterials are highlighted.

Indexed as

Biocompatible MaterialsNanostructuresNanotechnologyAnimalsHumansRegenerative MedicineTissue EngineeringBiocompatible Materialsbioimagingbiomaterialsdrug deliverynanoengineeringregenerative medicine

Identifiers

PMID40643040
PMCPMC12506621

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.