Evidence map›Paper›PMID 40642989›Full record

ArticleBiomarkers in medicine2025

Evaluation of the diagnostic efficacy of serum DR-70 and its combination with CEA in lung cancer.

Xuena Wang, Xianda Wei, Zifeng Cheng, Xu Zhou, Xiaoyun Lei, Wen Zhao, Qiuxing Tao, Zhilüe Lü, Hua Lin, Baoheng Gui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Xuena WangCenter for Medical Genetics and Genomics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xianda WeiCenter for Medical Genetics and Genomics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zifeng ChengThe Second School of Medicine, Guangxi Medical University, Nanning, China.
Xu ZhouThe Second School of Medicine, Guangxi Medical University, Nanning, China.
Xiaoyun LeiCenter for Medical Genetics and Genomics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Wen ZhaoCardiothoracic Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Qiuxing TaoThe Second School of Medicine, Guangxi Medical University, Nanning, China.
Zhilüe LüDepartment of Medical Laboratory, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Hua LinMedical Examination Center, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Baoheng GuiCenter for Medical Genetics and Genomics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the diagnostic value of DR-70 immunoassay and its combination with carcinoembryonic antigen (CEA) measurement for detecting lung malignancies.

methodsSerum concentrations of carcinoembryonic antigen (CEA) and DR-70 were quantitatively assessed using electrochemiluminescence immunoassay (ECLIA) and enzyme-linked immunosorbent assay (ELISA), in 110 patients diagnosed with primary lung cancer, 48 patients with pulmonary benign lesions, and 164 healthy subjects.

resultsSerum levels of both DR-70 and CEA showed statistically significant differences between lung cancer patients and healthy controls (

conclusionIndividual serum DR-70 testing and the combined DR-70+CEA panel exhibited robust diagnostic efficacy in lung adenocarcinoma detection.

Indexed as

Biomarkers, TumorCarcinoembryonic AntigenLung NeoplasmsAdultAgedCase-Control StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedROC CurveSensitivity and SpecificityWAP Four-Disulfide Core Domain Protein 2Biomarkers, TumorCarcinoembryonic AntigenWAP Four-Disulfide Core Domain Protein 2WFDC2 protein, humanCEAcombination of DR-70 and CEAdiagnostic efficacyDR-70lung adenocarcinoma

Identifiers

PMID40642989
PMCPMC12258205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.