Evidence map›Paper›PMID 40642650›Full record

ArticleSaudi journal of anaesthesia

Anesthetic management of a child with aromatic L-amino acid decarboxylase deficiency: A case report.

Rayan Muawad, Abdullah AlDhuwaihy, Abdulrahman AlGhamdi, Ahmed Abdurazaq

Abstract readCase Reports
In one paragraph

Article in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rayan MuawadPediatric Anesthesia Department, King Abdullah Specialist Children Hospital, Ministry of National Guard Health Affairs (MNGHA), Riyadh, Saudi Arabia.
Abdullah AlDhuwaihyCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdulrahman AlGhamdiCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ahmed AbdurazaqPediatric Anesthesia Department, King Abdullah Specialist Children Hospital, Ministry of National Guard Health Affairs (MNGHA), Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report discusses the anesthetic management of a 7-year-old child with aromatic L-amino acid decarboxylase (AADC) deficiency, a rare neurometabolic disorder. The patient underwent ventilation tube insertion and adenotonsillectomy. Similar to other adenotonsillectomy procedures, this surgery carries a higher risk of postoperative nausea and vomiting, necessitating a careful management strategy. We opted for dexamethasone as the primary antiemetic agent and limited opioid use to a single dose of fentanyl, while also incorporating dexmedetomidine for enhanced pain management alongside ketorolac and paracetamol. This case highlights the need for specialized anesthesia protocols for AADC deficiency patients to enhance safety and outcomes, particularly addressing the challenges of nausea and vomiting.

Indexed as

AADC deficiencydevelopmental delayhypotonianeurometabolic disorderspediatric anesthesia

Identifiers

PMID40642650
PMCPMC12240520

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.